Evidence map›Paper›PMID 29925807›Full record

ArticleMolecules (Basel, Switzerland)2018

Cytotoxic Triterpenes from

Laila S Espindola, Renata G Dusi, Daniel P Demarque, Raimundo Braz-Filho, Pengcheng Yan, Heidi R Bokesch, Kirk R Gustafson, John A Beutler

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Antitumoral Properties of Natural Products.Molecules (Basel, Switzerland) · 2020
    Article
  9. Molecules (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Laila S EspindolaLaboratório de Farmacognosia, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Brasília 70910-900, Brazil. darvenne@unb.br.
Renata G DusiLaboratório de Farmacognosia, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Brasília 70910-900, Brazil. renatadusi@hotmail.com.
Daniel P DemarqueLaboratório de Farmacognosia, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Brasília 70910-900, Brazil. dpdemarque@gmail.com.ORCID 0000-0002-3576-5148
Raimundo Braz-FilhoFAPERJ/Departamento de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ and Laboratório de Ciências Químicas, Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, Rio de Janeiro 28013-602, Brazil. braz@uenf.br.ORCID 0000-0001-7217-3494
Pengcheng YanMolecular Targets Program, National Cancer Institute, Frederick, MD 21702, USA. yanpc@wzmc.edu.cn.
Heidi R BokeschMolecular Targets Program, National Cancer Institute, Frederick, MD 21702, USA. bokeschh@mail.nih.gov.ORCID 0000-0003-4882-3316
Kirk R GustafsonMolecular Targets Program, National Cancer Institute, Frederick, MD 21702, USA. gustafki@mail.nih.gov.
John A BeutlerMolecular Targets Program, National Cancer Institute, Frederick, MD 21702, USA. beutlerj@mail.nih.gov.ORCID 0000-0002-4646-1924
Target (United States) · USLeidos (United States) · USUniversidade de Brasília · BRUniversidade Federal Rural do Rio de Janeiro · BR

Funding

Natural Products Discovery and Characterization Through Network CollaborationsZIABC011568 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI DU, LIN · 2014 to 2025
$17.2M
6 · The paper itself

Abstract

The new pentacyclic triterpene 11

Indexed as

Antineoplastic AgentsCelastraceaeCell Line, TumorCell SurvivalDrug Screening Assays, AntitumorHumansMetabolomicsPentacyclic TriterpenesPlant ExtractsPlant RootsSalaciaStructure-Activity RelationshipTriterpenesAntineoplastic AgentscelastrolPentacyclic TriterpenesPlant ExtractsTriterpenesBrazilian Cerrado biomeCelastraceaeCheiloclinium cognatumcytotoxic activityNCI-60 cancer cell linePlenckia populneapristimerinSalacia crassifoliaSalacia elliptica

Identifiers

PMID29925807
PMCPMC6099938
OpenAlexW2809683756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.