Evidence map›Paper›PMID 29925774›Full record

ArticleMarine drugs2018

Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota.

Erin K Crowley, Caitriona M Long-Smith, Amy Murphy, Elaine Patterson, Kiera Murphy, Denise M O'Gorman, Catherine Stanton, Yvonne M Nolan

Abstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.Clinical nutrition (Edinburgh, Scotland) · 2022
    Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Magnesium (MgCurrent pharmaceutical design · 2024
    Review
  11. Review
  12. Red Marine AlgaeMarine drugs · 2023
    Article
  13. Serum Magnesium is Inversely Associated with Body Composition and Metabolic Syndrome.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Article
  14. Antioxidant/anti-inflammatory effect of MgReviews in medical virology · 2022
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Erin K CrowleyDepartment of Anatomy and Neuroscience, University College Cork, T12XF62 Cork, Ireland. erin.crowley@ucc.ie.
Caitriona M Long-SmithDepartment of Anatomy and Neuroscience, University College Cork, T12XF62 Cork, Ireland. c.longsmith@ucc.ie.
Amy MurphyAPC Microbiome Ireland, Teagasc Food Research Centre, Moorepark, Fermoy, P61 C996 Cork, Ireland. amy.murphy@teagasc.ie.
Elaine PattersonAPC Microbiome Ireland, Teagasc Food Research Centre, Moorepark, Fermoy, P61 C996 Cork, Ireland. elainepatterson01@gmail.com.
Kiera MurphyAPC Microbiome Ireland, Teagasc Food Research Centre, Moorepark, Fermoy, P61 C996 Cork, Ireland. kieracmurphy@gmail.com.
Denise M O'GormanMarigot Ltd., Strand Farm, Currabinny, Carrigaline, P43NN62 Cork, Ireland. denise.ogorman@marigot.ie.
Catherine StantonAPC Microbiome Ireland, Teagasc Food Research Centre, Moorepark, Fermoy, P61 C996 Cork, Ireland. catherine.stanton@teagasc.ie.
Yvonne M NolanDepartment of Anatomy and Neuroscience, University College Cork, T12XF62 Cork, Ireland. y.nolan@ucc.ie.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence demonstrates that dietary supplementation with functional food ingredients play a role in systemic and brain health as well as in healthy ageing. Conversely, deficiencies in calcium and magnesium as a result of the increasing prevalence of a high fat/high sugar "Western diet" have been associated with health problems such as obesity, inflammatory bowel diseases, and cardiovascular diseases, as well as metabolic, immune, and psychiatric disorders. It is now recognized that modulating the diversity of gut microbiota, the population of intestinal bacteria, through dietary intervention can significantly impact upon gut health as well as systemic and brain health. In the current study, we show that supplementation with a seaweed and seawater-derived functional food ingredient rich in bioactive calcium and magnesium (0.1% supplementation) as well as 70 other trace elements, significantly enhanced the gut microbial diversity in adult male rats. Given the significant impact of gut microbiota on health, these results position this marine multi-mineral blend (MMB) as a promising digestive-health promoting functional food ingredient.

Indexed as

Dietary SupplementsFunctional FoodAnimalsBehavior, AnimalDNA, BacterialGastrointestinal MicrobiomeMaleMineralsModels, AnimalRatsRats, Sprague-DawleyRNA, Ribosomal, 16SSeaweedAquaminDNA, BacterialMineralsRNA, Ribosomal, 16Scalciumgut microbial diversitymagnesiummarine extractrat

Identifiers

PMID29925774
PMCPMC6024889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.