ArticleJournal of clinical microbiology2018
Droplet Digital PCR-Based Detection of Clarithromycin Resistance in Helicobacter pylori Isolates Reveals Frequent Heteroresistance.
Open access · bronzeAbstract read
In one paragraph
Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
6.2field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 4 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Global trends and research profile of antibiotic heteroresistance: a bibliometric and visual analysis.Frontiers in microbiology · 2026Pooled it
- The global prevalence of gastric cancer in Helicobacter pylori-infected individuals: a systematic review and meta-analysis.BMC infectious diseases · 2023Pooled it
- The prevalence of clarithromycin-resistantPeerJ · 2023Pooled it
- Heteroresistance to clarithromycin and metronidazole in patients with a Helicobacter pylori infection: a systematic review and meta-analysis.Annals of clinical microbiology and antimicrobials · 2022Pooled it
- Biofilm Formation and the Pore ProteinsAntibiotics (Basel, Switzerland) · 2026Article
- Clinical Evaluation of a Stool-Based Molecular Point-of-Care Test Kit for Noninvasive Detection of Helicobacter pylori Infection and Clarithromycin Resistance.Canadian journal of gastroenterology & hepatology · 2026Article
- Helicobacter pylori antimicrobial resistance and gene variants in Shandong Province.Scientific reports · 2025Article
- Colistin heteroresistance, mechanisms, diagnostic methods, and therapeutic options: A review.Germs · 2025Review
- Antibiotic resistance in Helicobacter pylori: a genetic and physiological perspective.Gut pathogens · 2025Review
- Efficacy and safety of Qingwei Zhitong pellets-containing quadruple therapy for eradication: a prospective, single-center, randomized trial.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025Article
- Comparative analysis of the detection of antibiotic genotypic resistance with gastric mucosa, gastric fluid, and fecal samples in patients withJournal of clinical microbiology · 2025Article
- Detection by Real-Time PCR ofMicroorganisms · 2024Article
- Article
- Antibiotic heteroresistance and persistence: an additional aid in hospital acquired infections byFuture microbiology · 2024Review
- Optical detection using CRISPR-Cas12a of Helicobacter pylori for veterinary applications.Mikrochimica acta · 2023Article
- The use of non-invasive stool tests for verification of Helicobacter pylori eradication and clarithromycin resistance.United European gastroenterology journal · 2023Article
- Drug-ResistantDiagnostics (Basel, Switzerland) · 2023Review
- Antibiotic Resistance Rates forMicroorganisms · 2023Article
- Diagnosis and Treatment ofDiagnostics (Basel, Switzerland) · 2023Review
- Molecular Mechanisms of Antibiotic Resistance and Novel Treatment Strategies forTropical medicine and infectious disease · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 2 countries.
Lu SunState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.ORCID 0000-0001-7041-1137
Sarah TalaricoHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Lena YaoVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Lihua HeState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Steve SelfVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Yuanhai YouState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Huifang ZhangState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yiyao ZhangState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yongjun GuoDepartment of Molecular Pathology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
Guodong LiuBeijing Centers for Disease Prevention and Control, Beijing, China.
Nina R SalamaHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA nsalama@fredhutch.org zhangjianzhong@icdc.cn.ORCID 0000-0003-2762-1424
Jianzhong ZhangState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China nsalama@fredhutch.org zhangjianzhong@icdc.cn.ORCID 0000-0001-7056-8206
National Institute for Communicable Disease Control and Prevention · CNFred Hutch Cancer Center · USBeijing Center for Disease Prevention and Control · CNZhengzhou University · CN
Funding
Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4MGENETIC REQUIREMENTS OF HELICOBACTER PYLORI INFECTIONR01AI054423 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Nina Salama · 2004 to 2026
$9.5MShared Host Genetics and Bacterial Adaptation in the Transmission of H. pyloriK01DK090103 · NIDDK · FRED HUTCHINSON CANCER RESEARCH CENTER · PI TALARICO, SARAH · 2012 to 2016
$501kNCI NIH HHS P30 CA015704NIAID NIH HHS R01 AI054423NIDDK NIH HHS K01 DK090103
Abstract
Chronic infection with
Indexed as
Polymerase Chain ReactionAdultAgedAnti-Bacterial AgentsClarithromycinDrug Resistance, BacterialFecesFemaleGastric MucosaGenetic VariationGenotypeHelicobacter InfectionsHelicobacter pyloriHumansMaleMicrobial Sensitivity TestsAnti-Bacterial AgentsClarithromycinRNA, Ribosomal, 23Sclarithromycin resistancedroplet digital PCRHelicobacter pyloriheteroresistancenoninvasive detection
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.