Evidence map›Paper›PMID 29925644›Full record

ArticleJournal of clinical microbiology2018

Multiplex PCR Analysis for Rapid Detection of Klebsiella pneumoniae Carbapenem-Resistant (Sequence Type 258 [ST258] and ST11) and Hypervirulent (ST23, ST65, ST86, and ST375) Strains.

Fangyou Yu, Jingnan Lv, Siqiang Niu, Hong Du, Yi-Wei Tang, Johann D D Pitout, Robert A Bonomo, Barry N Kreiswirth, Liang Chen

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

  1. RecCVirulence · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Risk factors forMicrobiology spectrum · 2026
    Article
  6. Differential virulence potential of different clades of multidrug-resistantmedRxiv : the preprint server for health sciences · 2026
    Article
  7. Epidemiological Insights into Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  8. Carriage of hypervirulent and ESBL-producingApplied and environmental microbiology · 2026
    Article
  9. Article
  10. Overcoming phagocytosis resistance of hypervirulentMicrobial cell (Graz, Austria) · 2026
    Article
  11. Hypervirulent and Drug-ResistantInternational journal of general medicine · 2026
    Review
  12. Article
  13. Multiplex PCR assay for the rapid detection ofJournal of medical microbiology · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Multidrug-resistant hypervirulentFuture microbiology · 2025
    Review
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fangyou Yu *Department of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Jingnan Lv *Department of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Siqiang NiuDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Hong DuDepartment of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Yi-Wei TangDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0003-4888-6771
Johann D D PitoutDepartment of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada.
Robert A BonomoCase VA Center for Antimicrobial Resistance and Epidemiology (CARES), Cleveland, Ohio, USA.
Barry N KreiswirthPublic Health Research Institute Tuberculosis Center, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA.
Liang ChenPublic Health Research Institute Tuberculosis Center, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA Chen11@njms.rutgers.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
The molecular basis of the epidemic blaKPC gene KlebsiellaR01AI090155 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI KREISWIRTH, BARRY NEAL · 2011 to 2021
$7.2M
Understanding B-Lactam Resistance in Acinetobacter baumanniiR01AI072219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ROBERT A. BONOMO, Philip N. Rather · 2007 to 2026
$6.6M
Understanding ceftazidime resistance in SHV B-LactamasesR01AI063517 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A. · 2005 to 2023
$4.9M
A Mechanism-Based Approach to Metallo-beta-Lactamase InhibitionR01AI100560 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A., SPENCER, JAMES · 2012 to 2022
$4.4M
Unraveling colistin resistance in Klebsiella pneumoniaeR21AI135250 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI KREISWIRTH, BARRY NEAL · 2018 to 2019
$460k
Molecular Epidemiology of Carbapenem-Resistant Klebsiella pneumoniaeR21AI114508 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A., VAN DUIN, DAVID · 2015 to 2016
$445k
Genomic variation in epidemic carbapenem-resistant K.pneumoniaeR21AI117338 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI CHEN, LIANG · 2016 to 2017
$437k
The Continuing Challenge of Carbapenemases in K. pneumoniae: KPC-2 & NDM-1I01BX001974 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI BONOMO, ROBERT A. · 2013 to 2024
–
BLRD VA I01 BX001974NCI NIH HHS P30 CA008748NIAID NIH HHS R01 AI063517NIAID NIH HHS R01 AI072219NIAID NIH HHS R01 AI090155NIAID NIH HHS R01 AI100560NIAID NIH HHS R21 AI114508NIAID NIH HHS R21 AI117338NIAID NIH HHS R21 AI135250
6 · The paper itself

Abstract

Carbapenem-resistant and hypervirulent

Indexed as

Multiplex Polymerase Chain ReactionAnti-Bacterial AgentsBacterial CapsulesCarbapenem-Resistant EnterobacteriaceaeCarbapenemsChinaDrug Resistance, BacterialGenes, BacterialGenotypeHumansKlebsiella InfectionsKlebsiella pneumoniaeMolecular Diagnostic TechniquesVirulenceAnti-Bacterial AgentsCarbapenemscapsular polysaccharidecarbapenem resistancehypervirulencemultiplex PCRplasmid

Identifiers

PMID29925644
PMCPMC6113471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.