Evidence map›Paper›PMID 29925643›Full record

ArticleJournal of clinical microbiology2018

Xpert Ultra Can Unambiguously Identify Specific Rifampin Resistance-Conferring Mutations.

Kamela C S Ng, Armand van Deun, Conor J Meehan, Gabriela Torrea, Michèle Driesen, Siemon Gabriëls, Leen Rigouts, Emmanuel André, Bouke C de Jong

Abstract readLetter
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Paucibacillary Tuberculosis Drives the Low Positive Predictive Value of Xpert MTB/RIF Ultra for Rifampicin Resistance Detection in Low-Prevalence Settings.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  5. Article
  6. Article
  7. Culture-Free Whole Genome Sequencing ofOpen forum infectious diseases · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Automatic Identification of IndividualJournal of clinical microbiology · 2019
    Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kamela C S NgUnit of Mycobacteriology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium kng@itg.be.ORCID 0000-0003-2049-3116
Armand van DeunUnit of Mycobacteriology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Conor J MeehanUnit of Mycobacteriology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0003-0724-8343
Gabriela TorreaUnit of Mycobacteriology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0001-7372-0859
Michèle DriesenUnit of Mycobacteriology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0002-4921-4988
Siemon GabriëlsUnit of Mycobacteriology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Leen RigoutsUnit of Mycobacteriology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0003-3301-9480
Emmanuel André *Laboratory of Clinical Bacteriology and Mycology, KU Leuven, Leuven, Belgium.ORCID 0000-0001-8321-3770
Bouke C de Jong *Unit of Mycobacteriology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0002-1017-4675

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibiotics, AntitubercularBacterial ProteinsDNA-Directed RNA PolymerasesDrug Resistance, BacterialHumansMolecular Diagnostic TechniquesMolecular ProbesMutationMycobacterium tuberculosisRifampinSensitivity and SpecificityTemperatureTuberculosisAntibiotics, AntitubercularBacterial ProteinsDNA-Directed RNA PolymerasesMolecular ProbesRifampinrpoB protein, Mycobacterium tuberculosisdisputed mutationsmelting temperature shift (ΔTm)melt peak temperature (Tm)rifampin-resistant tuberculosisrpoB mutationsUltra probesXpert MTB/RIF Ultra

Identifiers

PMID29925643
PMCPMC6113491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.