ArticleThe Journal of biological chemistry2018
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
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Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial.Respiratory research · 2023Trial
- Cathepsin C-driven enhancement of neutrophil extracellular trap formation contributes to acute lung injury.iScience · 2025Article
- Dipeptidyl peptidase 1 inhibitors and neutrophilic inflammation in bronchiectasis: a narrative review.Journal of thoracic disease · 2025Review
- Advances in the treatment of ANCA-associated vasculitis.Nature reviews. Rheumatology · 2025Review
- Dipeptidyl peptidase-1 inhibitors in bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Dipeptidyl peptidase 1 inhibitors for inflammatory respiratory diseases: mechanisms, clinical trials, and therapeutic prospects.Frontiers in pharmacology · 2025Review
- Cathepsin C inhibition reduces neutrophil serine protease activity and improves activated neutrophil-mediated disorders.Nature communications · 2024Article
- Cathepsin C from extracellular histone-induced M1 alveolar macrophages promotes NETosis during lung ischemia-reperfusion injury.Redox biology · 2024Article
- Neutrophil-Derived Proteases in Lung Inflammation: Old Players and New Prospects.International journal of molecular sciences · 2024Review
- Dipeptidyl peptidase 1 inhibition as a potential therapeutic approach in neutrophil-mediated inflammatory disease.Frontiers in immunology · 2023Review
- An optimized method of extracting and quantifying active Neutrophil serine proteases from human whole blood cells.PloS one · 2022Article
- Article
- Pathogenicity of Proteinase 3-Anti-Neutrophil Cytoplasmic Antibody in Granulomatosis With Polyangiitis: Implications as Biomarker and Future Therapies.Frontiers in immunology · 2021Review
- Neutrophil Extracellular Traps (NETs) Take the Central Stage in Driving Autoimmune Responses.Cells · 2020Review
- Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis.International journal of molecular sciences · 2019Article
- Biguanide is a modifiable pharmacophore for recruitment of endogenous ZnBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2019Review
- Papillon-Lefèvre Syndrome and Basal Cell Carcinoma: A Case Study.Case reports in oncologyArticle
Corrections and comments
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Authors and funding
32 authors at 15 institutions in 13 countries.
Seda SerenFrom the INSERM U-1100, "Centre d'Etude des Pathologies Respiratoires" and Université de Tours, 37000 Tours, France.
Maha Rashed Abouzaidthe Departments of Oro-Dental Genetics and.
Claudia Eulenberg-Gustavusthe Experimental and Clinical Research Center, Charité und Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC), 13125 Berlin, Germany.
Josefine Hirschfeldthe Institute of Clinical Sciences, College of Medical and Dental Sciences, Periodontal Research Group, University of Birmingham and Birmingham Community Health Trust, Edgbaston, Birmingham B5 7EG, United Kingdom.
Hala Nasr SolimanMedical Molecular Genetics, National Research Centre, Cairo 12622, Egypt.
Uwe Jerkethe Experimental and Clinical Research Center, Charité und Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC), 13125 Berlin, Germany.
Koffi N'GuessanFrom the INSERM U-1100, "Centre d'Etude des Pathologies Respiratoires" and Université de Tours, 37000 Tours, France.
Sandrine Dallet-ChoisyFrom the INSERM U-1100, "Centre d'Etude des Pathologies Respiratoires" and Université de Tours, 37000 Tours, France.
Adam Lesnerthe Faculty of Chemistry, University of Gdansk, 80-309 Gdansk, Poland.
Conni LauritzenUnizyme Laboratories A/S, 2970 Hørsholm, Denmark.
Beate Schacherthe Department of Periodontology, Johann Wolfgang Goethe-University Frankfurt, 60323 Frankfurt, Germany.
Peter Eickholzthe Department of Periodontology, Johann Wolfgang Goethe-University Frankfurt, 60323 Frankfurt, Germany.
Nikoletta Nagythe Department of Medical Genetics, University of Szeged, Szeged 6720, Hungary.
Marta Szellthe Department of Medical Genetics, University of Szeged, Szeged 6720, Hungary.
Cécile CroixUMR-CNRS 7292 "Génétique, Immunothérapie, Chimie et Cancer" and Université François Rabelais, 37000 Tours, France.
Marie-Claude Viaud-MassuardUMR-CNRS 7292 "Génétique, Immunothérapie, Chimie et Cancer" and Université François Rabelais, 37000 Tours, France.
Abdullah Al Farraj Aldosarithe Department of Prosthetic Dental Science, College of Dentistry, King Saud University, Riyadh 12372, Kingdom of Saudi Arabia.
Shivanna Ragunathathe Department of Dermatology, Venereology, and Leprosy, ESIC Medical College and PGIMSR Rajajinagar, Bengaluru, Karnataka 560010, India.
Mostafa Ibrahim Mostafathe Departments of Oro-Dental Genetics and.
Francesca Giampierithe Department of Clinical Sciences, Università Politecnica delle Marche, 60121 Ancona, Italy.ORCID 0000-0002-8151-9132
Maurizio Battinothe Department of Clinical Sciences, Università Politecnica delle Marche, 60121 Ancona, Italy.
Hélène CornillierService de Dermatologie, Centre Hospitalier Universitaire de Tours, Université de Tours, 37000 Tours, France.
Gérard LoretteUMR-INRA1282 "Laboratoire de Virologie et Immunologie Moléculaires," Université de Tours, 37000 Tours, France.
Jean-Louis Stephanthe Service d'Hématologie Immunologie et Rhumatologie Pédiatrique, Centre Hospitalier Universitaire de Saint-Etienne, 42270 Saint-Priest-en-Jarez, France.
Cyril GoizetINSERM U-1211, Rare Diseases, Genetic and Metabolism, MRGM Laboratory, Pellegrin Hospital and University, 33000 Bordeaux, France.
John PedersenUnizyme Laboratories A/S, 2970 Hørsholm, Denmark.
Francis GauthierFrom the INSERM U-1100, "Centre d'Etude des Pathologies Respiratoires" and Université de Tours, 37000 Tours, France.
Dieter E Jennethe Comprehensive Pneumology Center, Institute of Lung Biology and Disease, German Center for Lung Research (DZL), 81377 Munich, Germany.
Sylvain Marchand-AdamFrom the INSERM U-1100, "Centre d'Etude des Pathologies Respiratoires" and Université de Tours, 37000 Tours, France.
Iain L Chapplethe Institute of Clinical Sciences, College of Medical and Dental Sciences, Periodontal Research Group, University of Birmingham and Birmingham Community Health Trust, Edgbaston, Birmingham B5 7EG, United Kingdom.
Ralph Kettritzthe Experimental and Clinical Research Center, Charité und Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC), 13125 Berlin, Germany.
Brice KorkmazFrom the INSERM U-1100, "Centre d'Etude des Pathologies Respiratoires" and Université de Tours, 37000 Tours, France, brice.korkmaz@inserm.fr.ORCID 0000-0002-5159-8706
Université de Tours · FRHelmholtz Association of German Research Centres · DEGoethe University Frankfurt · DEMarche Polytechnic University · ITNovozymes (Denmark) · DKPediatrics and Genetics · USUniversity of Birmingham · GBUniversity of Szeged · HUESI - Post Graduate Institute of Medical Science and Research · INGerman Center for Lung Research · DEInserm · FRInstitute Cancer De La Loire Lucien Neuwirth · FRKing Saud University · SANational Research Centre · EGUniversity of Gdańsk · PL
Funding
No grant is acknowledged in the PubMed record.
Abstract
Membrane-bound proteinase 3 (PR3
Indexed as
AdolescentAdultCase-Control StudiesCathepsin CCell MembraneChildChild, PreschoolCysteine Proteinase InhibitorsFemaleGranulomatosis with PolyangiitisHumansMaleMyeloblastinNeutrophilsProteolysisYoung AdultCathepsin CCTSC protein, humanCysteine Proteinase InhibitorsMyeloblastinaminopeptidaseantigenautoimmune diseasecathepsin Cgenetic diseasegranulomatosis with polyangiitisneutrophilPapillon-Lefèvre syndromeproteaseprotease inhibitorproteinase 3
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.