Evidence map›Paper›PMID 29925569›Full record

ArticleRNA (New York, N.Y.)2018

Fitness advantages conferred by the L20-interacting RNA

Arianne M Babina, Darren J Parker, Gene-Wei Li, Michelle M Meyer

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Extraribosomal Functions of Bacterial Ribosomal Proteins-An Update, 2023.International journal of molecular sciences · 2024
    Review
  2. Article
  3. Article
  4. An RNA-centric global view ofProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  5. Article
  6. Autogenous regulation in vivo of theRNA (New York, N.Y.) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Arianne M BabinaDepartment of Biology, Boston College, Chestnut Hill, Massachusetts 02467, USA.
Darren J ParkerDepartment of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Gene-Wei LiDepartment of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Michelle M MeyerDepartment of Biology, Boston College, Chestnut Hill, Massachusetts 02467, USA.ORCID 0000-0001-7014-9271
Boston College · USMassachusetts Institute of Technology · US

Funding

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8M
Evolutionary forces that maintain structured RNA regulators in commensal and pathogenic bacteriaR01GM115931 · NIGMS · BOSTON COLLEGE · PI MEYER, MICHELLE MARGARET, VAN OPIJNEN, TIM · 2015 to 2018
$1.2M
NIGMS NIH HHS R01 GM115931NIGMS NIH HHS T32 GM007287
6 · The paper itself

Abstract

In many bacteria, ribosomal proteins autogenously repress their own expression by interacting with RNA structures typically located in the 5'-UTRs of their mRNA transcripts. This regulation is necessary to maintain a balance between ribosomal proteins and rRNA to ensure proper ribosome production. Despite advances in noncoding RNA discovery and validation of RNA-protein regulatory interactions, the selective pressures that govern the formation and maintenance of such RNA

Indexed as

Point MutationBacillus subtilisBacterial ProteinsGenetic FitnessMicrobial ViabilityNucleic Acid ConformationProtein BindingRibosomal ProteinsRNA, BacterialRNA, MessengerRNA, RibosomalBacterial ProteinsL20 ribosomal protein, bacteriaRibosomal ProteinsRNA, BacterialRNA, MessengerRNA, Ribosomalfitnessgene regulationribosomal proteinribosome assemblyRNA cis-regulatorrRNA

Identifiers

PMID29925569
PMCPMC6097659
OpenAlexW2809434207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.