Evidence map›Paper›PMID 29925565›Full record

ArticleGenetics2018

Regulators of Long-Term Memory Revealed by Mushroom Body-Specific Gene Expression Profiling in

Yves F Widmer, Adem Bilican, Rémy Bruggmann, Simon G Sprecher

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  11. The Making of Long-Lasting Memories: A Fruit Fly Perspective.Frontiers in behavioral neuroscience · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. DamID as a versatile tool for understanding gene regulation.Development (Cambridge, England) · 2019
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yves F WidmerDepartment of Biology, University of Fribourg, CH-1700, Switzerland.
Adem BilicanInterfaculty Bioinformatics Unit, University of Bern, CH-3012, Switzerland.
Rémy BruggmannInterfaculty Bioinformatics Unit, University of Bern, CH-3012, Switzerland.
Simon G SprecherDepartment of Biology, University of Fribourg, CH-1700, Switzerland simon.sprecher@unifr.ch.
University of Bern · CHUniversity of Fribourg · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Memory formation is achieved by genetically tightly controlled molecular pathways that result in a change of synaptic strength and synapse organization. While for short-term memory traces, rapidly acting biochemical pathways are in place, the formation of long-lasting memories requires changes in the transcriptional program of a cell. Although many genes involved in learning and memory formation have been identified, little is known about the genetic mechanisms required for changing the transcriptional program during different phases of long-term memory (LTM) formation. With

Indexed as

Memory, Long-TermAnimalsAnimals, Genetically ModifiedBehavior, AnimalDrosophila melanogasterDrosophila ProteinsEnoyl-CoA HydrataseGene Expression ProfilingGene Expression Regulation, DevelopmentalGene Knockdown TechniquesMushroom BodiesOrgan SpecificityRNA InterferenceDrosophila ProteinsEnoyl-CoA HydrataseHacd1 protein, Drosophilavajk-1protein, DrosophilaDrosophila melanogasterlearninglong-term memorytargeted DamIDtranscriptome

Identifiers

PMID29925565
PMCPMC6063240
OpenAlexW2809357194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.