ArticleVeterinary research2018
Elevated faecal ovotransferrin concentrations are indicative for intestinal barrier failure in broiler chickens.
Article in Veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Using Gut Microbiota and Gut Metabolites as Biomarkers for Diseases in Monogastric Farm Animals.Animals : an open access journal from MDPI · 2026Review
- A NEW FOCUS ON FIBER.Poultry science · 2026Review
- Proteomic profiling of dysbiosis-challenged broilers reveals potential blood biomarkers for intestinal health.Veterinary research · 2025Article
- Comprehensive analysis of blood proteome response to necrotic enteritis in broiler chicken.Veterinary research · 2025Article
- Blood proteome profiling for biomarker discovery in broilers with necrotic enteritis.Scientific reports · 2025Article
- Impact of partially defatted black soldier fly larvae meal on coccidia-infected chickens: effects on growth performance, intestinal health, and cecal short-chain fatty acid concentrations.Journal of animal science and biotechnology · 2025Article
- Investigation of Potential Gut Health Biomarkers in Broiler Chicks Challenged byPathogens (Basel, Switzerland) · 2024Article
- Retrospective evaluation of acid-base imbalances, clinicopathologic alterations, and prognostic factors in hospitalized calves with Eimeria-associated diarrhea.Frontiers in veterinary science · 2024Article
- Poultry gut health and beyond.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- Identifying the shortfalls of crude protein-reduced, wheat-based broiler diets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Review
- Morphological Assessment and Biomarkers of Low-Grade, Chronic Intestinal Inflammation in Production Animals.Animals : an open access journal from MDPI · 2022Review
- Centennial Review: Factors affecting the chicken gastrointestinal microbial composition and their association with gut health and productive performance.Poultry science · 2022Review
- Current experimental models, assessment and dietary modulations of intestinal permeability in broiler chickens.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Review
- Novel Models for Chronic Intestinal Inflammation in Chickens: Intestinal Inflammation Pattern and Biomarkers.Frontiers in immunology · 2021Article
- Excreta biomarkers in response to different gut barrier dysfunction models and probiotic supplementation in broiler chickens.PloS one · 2020Article
- Disruption of gut integrity and permeability contributes to enteritis in a fish-parasite model: a story told from serum metabolomics.Parasites & vectors · 2019Article
- Host intestinal biomarker identification in a gut leakage model in broilers.Veterinary research · 2019Article
- Investigating Gut Permeability in Animal Models of Disease.Frontiers in physiology · 2018Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intestinal health is critically important for the welfare and performance of poultry. Enteric diseases that cause gut barrier failure result in high economic losses. Up till now there is no reliable faecal marker to measure gut barrier failure under field conditions. Therefore, the aim of the present study was to identify a faecal protein marker for diminished intestinal barrier function due to enteric diseases in broilers. To assess this, experimental necrotic enteritis and coccidiosis in broilers were used as models for gut barrier failure. Ovotransferrin was identified as a marker for gut barrier failure using a proteomics approach on samples from chickens with necrotic enteritis. These results were confirmed via ELISA on samples derived from both necrotic enteritis and coccidiosis trials, where faecal ovotransferrin levels were significantly correlated with the severity of gut barrier failure caused by either coccidiosis or necrotic enteritis. This indicates that faecal ovotransferrin quantification may represent a valuable tool to measure gut barrier failure caused by enteric pathogens.
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