Evidence map›Paper›PMID 29925397›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2018

Right heart catheterization using metallic guidewires and low SAR cardiovascular magnetic resonance fluoroscopy at 1.5 Tesla: first in human experience.

Adrienne E Campbell-Washburn, Toby Rogers, Annette M Stine, Jaffar M Khan, Rajiv Ramasawmy, William H Schenke, Delaney R McGuirt, Jonathan R Mazal, Laurie P Grant, Elena K Grant and 2 more

Registry-linked trialOpen access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03152773 (Heart Catheterization Using Magnetic Resonance Imaging), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03152773 naterminatednot on this map

Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires

TypeinterventionalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran2017 to 2021Enrolled22ConditionsPulmonary Artery Hypertension, Congenital Heart Disease, Structural Heart DiseaseArmsMRI Heart guidewire catheterization
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Interventional cardiovascular magnetic resonance: state-of-the-art.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Real-Time Magnetic Resonance Imaging.Journal of magnetic resonance imaging : JMRI · 2022
    Review
  10. Article
  11. Native contrast visualization and tissue characterization of myocardial radiofrequency ablation and acetic acid chemoablation lesions at 0.55 T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Journal of Cardiovascular Magnetic Resonance: 2017/2018 in review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019
    Review
  18. Article
  19. Article
  20. Cardiovascular magnetic resonance-guided right heart catheterization in a conventional CMR environment - predictors of procedure success and duration in pulmonary artery hypertension.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Adrienne E Campbell-WashburnCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA. adrienne.campbell@nih.gov.
Toby RogersCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
Annette M StineCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
Jaffar M KhanCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
Rajiv RamasawmyCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
William H SchenkeCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
Delaney R McGuirtCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
Jonathan R MazalCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
Laurie P GrantCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
Elena K GrantCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
Daniel A HerzkaCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
Robert J LedermanCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 2C713, Bethesda, MD, 20892-1538, USA.
National Institutes of Health · USNational Heart Lung and Blood Institute · US

Funding

Real-time MRI guided cardiovascular interventionZIAHL005062 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2009 to 2025
$21.6M
Diagnostic and interventional cardiovascular catheterizationZIDHL006061 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2010 to 2025
$18.2M
Real-time cardiovascular MRI and co-registration technical developmentZIAHL006039 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2010 to 2024
$10.3M
Gadgetron Global Network and Intelligence Computing: Clinical Imaging Application Development and Software InfrastructureZIAHL006214 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KELLMAN, PETER · 2016 to 2025
$7.3M
Therapies enabled-cardiovascular interventional MRIZ01HL005062 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2003 to 2008
$6.0M
Innovative Technology for MRI Guided ProceduresZIAHL006213 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CAMPBELL-WASHBURN, ADRIENNE · 2016 to 2025
$5.4M
Division of Intramural Research, National Heart Lung and Blood Institute Z01-HL006061Intramural NIH HHS Z01 HL005062Intramural NIH HHS ZIA HL006213
6 · The paper itself

Abstract

backgroundCardiovascular magnetic resonance (CMR) fluoroscopy allows for simultaneous measurement of cardiac function, flow and chamber pressure during diagnostic heart catheterization. To date, commercial metallic guidewires were considered contraindicated during CMR fluoroscopy due to concerns over radiofrequency (RF)-induced heating. The inability to use metallic guidewires hampers catheter navigation in patients with challenging anatomy. Here we use low specific absorption rate (SAR) imaging from gradient echo spiral acquisitions and a commercial nitinol guidewire for CMR fluoroscopy right heart catheterization in patients.

methodsThe low-SAR imaging protocol used a reduced flip angle gradient echo acquisition (10° vs 45°) and a longer repetition time (TR) spiral readout (10 ms vs 2.98 ms). Temperature was measured in vitro in the ASTM 2182 gel phantom and post-mortem animal experiments to ensure freedom from heating with the selected guidewire (150 cm × 0.035″ angled-tip nitinol Terumo Glidewire). Seven patients underwent CMR fluoroscopy catheterization. Time to enter each chamber (superior vena cava, main pulmonary artery, and each branch pulmonary artery) was recorded and device visibility and confidence in catheter and guidewire position were scored on a Likert-type scale.

resultsNegligible heating (< 0.07°C) was observed under all in vitro conditions using this guidewire and imaging approach. In patients, chamber entry was successful in 100% of attempts with a guidewire compared to 94% without a guidewire, with failures to reach the branch pulmonary arteries. Time-to-enter each chamber was similar (p=NS) for  the two approaches. The guidewire imparted useful catheter shaft conspicuity and enabled interactive modification of catheter shaft stiffness, however, the guidewire tip visibility was poor.

conclusionsUnder specific conditions, trained operators can apply low-SAR imaging and using a specific fully-insulated metallic nitinol guidewire (150 cm × 0.035" Terumo Glidewire) to augment clinical CMR fluoroscopy right heart catheterization.

trial registrationClinicaltrials.gov NCT03152773 , registered May 15, 2017.

Indexed as

Cardiac CathetersAlloysAnimalsCardiac CatheterizationEquipment DesignHot TemperatureHumansMagnetic Resonance Imaging, InterventionalMaterials TestingModels, AnimalPhantoms, ImagingPredictive Value of TestsSus scrofaTime FactorsWorkflowAlloysnitinolCardiac cathetersCardiovascular magnetic resonanceGuidewireInterventional MRI catheterizationInvasive hemodynamicsMedical device heatingReal-time MRIRight heart catheterizationSpiral MRI

Identifiers

PMID29925397
PMCPMC6011242
OpenAlexW2808439985

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.