Evidence map›Paper›PMID 29925323›Full record

ArticleBMC family practice2018

Risk of opioid misuse in chronic non-cancer pain in primary care patients - a cross sectional study.

Johannes Maximilian Just, Linda Bingener, Markus Bleckwenn, Rieke Schnakenberg, Klaus Weckbecker

Open access · goldAbstract read
In one paragraph

Article in BMC family practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Managing opioid use disorder in primary care: PEER simplified guideline.Canadian family physician Medecin de famille canadien · 2019
    Guideline
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Opioid epidemic and liver disease.JHEP reports : innovation in hepatology · 2019
    Review
  8. Canadian family physician Medecin de famille canadien · 2019
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Johannes Maximilian JustInstitute of General Practice and Family Medicine, Bonn University Clinic, Sigmund-Freud-Street 25, 53127, Bonn, Germany. johannes.just@ukbonn.de.ORCID 0000-0003-0866-5480
Linda BingenerInstitute of General Practice and Family Medicine, Bonn University Clinic, Sigmund-Freud-Street 25, 53127, Bonn, Germany.
Markus BleckwennInstitute of General Practice and Family Medicine, Bonn University Clinic, Sigmund-Freud-Street 25, 53127, Bonn, Germany.
Rieke SchnakenbergInstitute of General Practice and Family Medicine, Bonn University Clinic, Sigmund-Freud-Street 25, 53127, Bonn, Germany.
Klaus WeckbeckerInstitute of General Practice and Family Medicine, Bonn University Clinic, Sigmund-Freud-Street 25, 53127, Bonn, Germany.
University Hospital Bonn · DECarl von Ossietzky Universität Oldenburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEfforts to improve treatment of pain using opioids have to adequately take into account their therapeutic shortcomings which involve addictiveness. While there are no signs of an "opioid epidemic" in Germany similar to that in the US, there is little data on the prevalence of prescription opioid misuse and addiction. Therefore, our objective was to screen primary care patients on long-term opioid therapy for signs of misuse of prescription opioids.

methodsWe recruited 15 GPs practices and asked all patients on long-term opioid therapy (> 6 months) to fill out a questionnaire including the "Current Opioid Misuse Measure" (COMM®), a self-report questionnaire. Patients with a malignant disease were excluded.

resultsN = 91 patients participated in the study (response rate: 75.2%). A third (31.5%) showed a positive COMM® - Score which represents a high risk of aberrant drug behaviour. A positive COMM® - Score showed a statistically significant correlation with a lifetime diagnosis of depression and neck pain.

conclusionsWhile Germany does not face an "opioid eoidemic", addictiveness of opioids should be considered when using them in chronic non-tumor pain. In our study population, almost every third patient was at risk and should therefore be followed up closely. Co-prevalence of depression is a significant issue and should always be screened for in patients with chronic pain, especially thus with aberrant drug behaviour.

Indexed as

Analgesics, OpioidChronic PainDepressionOpioid-Related DisordersPrescription Drug MisusePrimary Health CareFemaleGermanyHumansMaleMiddle AgedNeeds AssessmentRisk AdjustmentRisk FactorsSelf ReportSurveys and QuestionnairesAnalgesics, OpioidAddictionMisuseOpioidPrescription drugsPrevalence

Identifiers

PMID29925323
PMCPMC6011396
OpenAlexW2809020134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.