ReviewAnnual review of biochemistry2018
Reductionist Approach in Peptide-Based Nanotechnology.
Review in Annual review of biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Chiral Glass Formation by Dipeptide Salts.Biomacromolecules · 2026Article
- Sequence-Dependent Heterotypic Assemblies of Intrinsically Disordered Peptides.ChemistryEurope · 2026Article
- Minimalistic Peptide Nanocarriers for Multiple Cancer Drugs.ACS applied bio materials · 2025Article
- Stimuli-Responsive Hydrogels from Liquid-Liquid Phase Separations of FUS-Derived Peptides.ACS applied materials & interfaces · 2025Article
- Article
- Cryo-EM for atomic characterization of supramolecular gels.Faraday discussions · 2025Article
- Small Peptide Derived from SFRP5 Suppresses Melanogenesis by Inhibiting Wnt Activity.Current issues in molecular biology · 2024Article
- Co-Assembly of Cancer Drugs with Cyclo-HH Peptides: Insights from Simulations and Experiments.ACS applied bio materials · 2024Article
- Computational analysis of protein synthesis, diffusion, and binding in compartmental biochips.Microbial cell factories · 2023Article
- Modified Smoluchowski Rate Equations for Aggregation and Fragmentation in Finite Systems.The journal of physical chemistry. B · 2023Article
- Peptide Self-Assembled Nanocarriers for Cancer Drug Delivery.The journal of physical chemistry. B · 2023Review
- Glycosylation of bacterial antigens changes epitope patterns.Frontiers in immunology · 2023Article
- Peptide framework for screening the effects of amino acids on assembly.Science advances · 2022Article
- The Peptidyl Transferase Center: a Window to the Past.Microbiology and molecular biology reviews : MMBR · 2021Article
- Fluorescence Emission of Self-assembling Amyloid-like Peptides: Solution versus Solid State.Chemphyschem : a European journal of chemical physics and physical chemistry · 2021Article
- From structure to application: Progress and opportunities in peptide materials development.Current opinion in chemical biology · 2021Review
- Diverse Aggregation Kinetics Predicted by a Coarse-Grained Peptide Model.The journal of physical chemistry. B · 2021Article
- Functionalized Prion-Inspired Amyloids for Biosensor Applications.Biomacromolecules · 2021Article
- Supramolecular Assembly and Chirality of Synthetic Carbohydrate Materials.Angewandte Chemie (International ed. in English) · 2020Article
- Enzymatic Noncovalent Synthesis.Chemical reviews · 2020Review
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Authors and funding
1 author.
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No grant is acknowledged in the PubMed record.
Abstract
The formation of ordered nanostructures by molecular self-assembly of proteins and peptides represents one of the principal directions in nanotechnology. Indeed, polyamides provide superior features as materials with diverse physical properties. A reductionist approach allowed the identification of extremely short peptide sequences, as short as dipeptides, which could form well-ordered amyloid-like β-sheet-rich assemblies comparable to supramolecular structures made of much larger proteins. Some of the peptide assemblies show remarkable mechanical, optical, and electrical characteristics. Another direction of reductionism utilized a natural noncoded amino acid, α-aminoisobutryic acid, to form short superhelical assemblies. The use of this exceptional helix inducer motif allowed the fabrication of single heptad repeats used in various biointerfaces, including their use as surfactants and DNA-binding agents. Two additional directions of the reductionist approach include the use of peptide nucleic acids (PNAs) and coassembly techniques. The diversified accomplishments of the reductionist approach, as well as the exciting future advances it bears, are discussed.
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