ArticlePloS one2018
Association between dry eye symptoms and suicidal ideation in a Korean adult population.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 6 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 6 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Decoding and reconstructing disease relations between dry eye and depression: a multimodal investigation comprising meta-analysis, genetic pathways and Mendelian randomization.Journal of advanced research · 2025Pooled it
- TFOS lifestyle: Impact of societal challenges on the ocular surface.The ocular surface · 2023Pooled it
- Dry eye disease and psychiatric disorders: A systematic review and meta-analysis.European journal of ophthalmology · 2022Pooled it
- Association between dry eye disease and depression: An umbrella review.Frontiers in public health · 2022Pooled it
- Work productivity among Sjögren's Syndrome and non-Sjögren's dry eye patients: a systematic review and meta-analysis.Eye (London, England) · 2021Pooled it
- A systematic review assessing the quality of patient reported outcomes measures in dry eye diseases.PloS one · 2021Pooled it
- A Scoping Review of Pharmacologic and Nonpharmacologic Interventions to Treat Chronic Ocular Pain.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2026Article
- Experts Perspectives on Current Practices and Challenges of Diagnosis and Treatment of Dry Eye Disease across Europe and Central Asia.Ophthalmology and therapy · 2026Article
- Central Nervous System Mechanisms and Treatment Response in Chronic Ocular Surface Pain: Protocol for a Cross-Sectional Observational Phenotyping Study.JMIR research protocols · 2026Observational
- A comprehensive analysis of dry eye disease clinical trials (2000-2024): research trends and gaps.Frontiers in pharmacology · 2026Article
- Chronic Ocular Surface Pain: An Optometrist and Ophthalmologist Survey.Ophthalmology and therapy · 2025Article
- Ocular surface changes and corneal epithelial remodeling after cataract surgery in patients with type 2 diabetes: a case-control study.BMC ophthalmology · 2025Article
- Symptomology and Impact of Dry Eye Disease: A Patient and Physician Perspective.Ophthalmology and therapy · 2025Article
- The Relationship Between Anxiety Sensitivity, Emotional States, and Dry Eye Disease Symptom Severity: A Cross-Sectional Study.Vision (Basel, Switzerland) · 2025Article
- Article
- Body constitutions of traditional Chinese medicine caused a significant effect on irritable bowel syndrome.Journal of the Chinese Medical Association : JCMA · 2024Article
- Rasch development and validation of the "Medellín Dry Eye Inventory" (ME·Dry), an instrument to measure multidimensional quality of life compromise in patients with dry eye disease.Indian journal of ophthalmology · 2023Article
- Article
- Association of Dry Eye Diseases and Auditory Sensitivity.Journal of clinical medicine · 2022Article
- Sleep disorders, mental health, and dry eye disease in South Korea.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study assessed the association of dry eyes with depression and suicidal ideation in a Korean adult population.
methodsData from 16408 participants (6972 men and 9436 women) aged ≥ 19 years included in the fifth Korea National Health and Nutrition Examination Survey, conducted from 2010-2012, were analyzed. For dry eyes, surveys of previous diagnosis of dry eye disease (DED) by an ophthalmologist and experience of subjective dry eye symptoms were separately used. Diagnosis of depression and suicidal ideation were obtained via responses to an interviewer-assisted questionnaire, and questions were asked in a closed-ended response format. Logistic regression was used to examine the associations between dry eyes, depression, and suicidal ideation.
resultsDED diagnosis exhibited an odds ratio (OR) of 1.32 (95% confidence interval [CI] 1.11-1.57) for depression and 1.24 (95% CI 1.05-1.48) for suicidal ideation compared to those without DED, after adjusting for sex, age, education, occupation, household income, body mass index, smoking behavior, alcohol consumption, physical activity, hypertension, diabetes, dyslipidemia, thyroid diseases, major cardiovascular disease, and cancer. Similarly, the adjusted OR (95% CI) of dry eye symptoms was 1.50 (95% CI 1.30-1.73) for depression and 1.47 (95% CI 1.27-1.70) for suicidal ideation.
conclusionOur findings suggest that dry eyes (either DED diagnosis or dry eye symptoms) may be associated with the prevalence of depression and suicidal ideation in the Korean adult population.
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