Evidence map›Paper›PMID 29924443›Full record

ArticleEuropean journal of neurology2018

Influence of lung function and sleep-disordered breathing on stroke: a community-based study.

J Zhang, Z Gong, R Li, Y Gao, Y Li, J Li, B Yan, G Wang

Abstract read
In one paragraph

Article in European journal of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Neck Circumference is Associated with Incidence of Angina Pectoris in a Large Community-Based Population.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  6. Incidence of Stroke and Mortality in Chinese Patients with Sleep-Breathing Disorders: A Clinical Population-Based (CPB) Study.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

J ZhangDepartment of Emergency Medicine, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Z GongXi'an Jiaotong University Health Science Centre, Xi'an, China.
R LiDepartment of Emergency Medicine, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Y GaoDepartment of Emergency Medicine, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Y LiDepartment of Rehabilitation, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
J LiDepartment of Emergency Medicine, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
B YanClinical Research Center of the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
G WangDepartment of Emergency Medicine, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-5905-7760
Second Affiliated Hospital of Xi'an Jiaotong University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNXi'an Jiaotong University · CN

Funding

DATA COORDINATING CENTER FOR SLEEP HEART STUDYU01HL064360 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI DIENER-WEST, MARIE · 1999 to 2007
$4.4M
The Sleep Heart Health Study (SHHS)U01HL053938 · NHLBI · UNIVERSITY OF ARIZONA · PI QUAN, STUART F. · 1994 to 2007
$2.0M
SLEEP HEART HEALTH STUDYU01HL053931 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RAPOPORT, DAVID M. · 1994 to 2003
$1.9M
THE SLEEP HEART HEALTH STUDYU01HL053937 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI PUNJABI, NARESH · 1994 to 2007
$1.6M
SLEEP HEART HEALTH STUDYU01HL053916 · NHLBI · UNIVERSITY OF CALIFORNIA DAVIS · PI ROBBINS, JOHN A · 1994 to 2007
$1.5M
THE SLEEP HEART HEALTH STUDYU01HL053934 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SHAHAR, EYAL · 1994 to 2007
$1.4M
SLEEP HEART HEALTH STUDYU01HL053941 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI O'CONNOR, GEORGE T · 1994 to 2007
$1.4M
NHLBI NIH HHS U01 HL053916NHLBI NIH HHS U01 HL053931NHLBI NIH HHS U01 HL053934NHLBI NIH HHS U01 HL053937NHLBI NIH HHS U01 HL053938NHLBI NIH HHS U01 HL053941NHLBI NIH HHS U01 HL064360NIH HHS U01HL53916NIH HHS U01HL53931NIH HHS U01HL53934NIH HHS U01HL53937NIH HHS U01HL53938NIH HHS U01HL53940NIH HHS U01HL53941NIH HHS U01HL64360
6 · The paper itself

Abstract

background and purposeImpaired lung function is regarded as a risk factor for stroke in patients with chronic obstructive pulmonary disease. However, the association between reduced lung function and incident stroke in a community-based population with sleep-disordered breathing (SDB) remains unknown.

methodsA prospective study was performed within the Sleep Heart Health Study cohort. Full montage home sleep testing and spirometry data on 2082 and 2072 individuals with and without SDB, respectively, were analysed. Cox proportional hazards regression models were used to estimate the association between lung function and incident stroke.

resultsOver 11.7 years, 183 cases of stroke were identified in participants without pre-existing cardiovascular diseases, including 71 and 112 with an apnoea-hypopnoea index <5 events/h and ≥5 events/h, respectively. In the entire population, lung function was inversely associated with incident stroke [hazard ratio (HR) 0.913 (95% confidence interval 0.839-0.994) for every 10% increase in percentage of predicted forced vital capacity]. When the population was divided according to the presence/absence of SDB, the association of lung function with incident stroke became stronger in individuals with SDB [HR 0.899 (0.822-0.984) for every 10% increase in percentage of predicted forced expiratory volume in 1 s; HR 0.881 (0.787-0.987) for every 10% increase in percentage of predicted forced vital capacity] but not in individuals without SDB.

conclusionsLung function may serve as a risk factor for incident stroke in a community-based population, especially in those with SDB. Spirometry may help improve the risk management for primary care in community-based populations.

Indexed as

AgedComorbidityFemaleHumansIncidenceLungMaleMiddle AgedPolysomnographyProspective StudiesRiskSleep Apnea SyndromesStrokecohort studycommunitylung functionsleep-disordered breathingstroke

Identifiers

PMID29924443
PMCPMC6181793
OpenAlexW2809349895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.