Evidence map›Paper›PMID 29924378›Full record

ArticleCardiology journal2020

The atherogenic index of plasma and its impact on recanalization of chronic total occlusion.

Jan-Erik Guelker, Alexander Bufe, Christian Blockhaus, Knut Kroeger, Thomas Rock, Ibrahim Akin, Michael Behnes, Kambis Mashayekhi

Open access · goldAbstract read
In one paragraph

Article in Cardiology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jan-Erik GuelkerHelios Clinic Krefeld, Lutherplatz 40, 47805 Krefeld, Germany. jan-erik.guelker@helios-kliniken.de.
Alexander BufeHelios Clinic Krefeld, Lutherplatz 40, 47805 Krefeld, Germany.
Christian BlockhausHelios Clinic Krefeld, Lutherplatz 40, 47805 Krefeld, Germany.
Knut KroegerHelios Clinic Krefeld, Lutherplatz 40, 47805 Krefeld, Germany.
Thomas RockHelios Clinic Krefeld, Lutherplatz 40, 47805 Krefeld, Germany.
Ibrahim Akin1st Medical Department, University Medical Centre Mannheim, Medical Faculty Mannheim, University of Heidelberg, Germany.
Michael Behnes1st Medical Department, University Medical Centre Mannheim, Medical Faculty Mannheim, University of Heidelberg, Germany.
Kambis MashayekhiDivision of Cardiology and Angiology II, University Heart Center Freiburg • Bad Krozingen.
Helios Klinikum Krefeld · DEHeidelberg University · DEUniversitäts-Herzzentrum Freiburg-Bad Krozingen · DEUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe plasma-derived atherogenic index (AIP) is associated with an increasing risk for cardiovascular diseases. Whether an increased AIP may predict the complexity of percutaneous coronary intervention (PCI) of chronic total occlusion (CTO), according to available research, has never been investigated before.

methodsThree hundred seventeen patients were included prospectively and treated with PCI for at least one CTO between 2012 and 2017. High-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) plasma levels were measured 24 h before PCI. All patients were stratified into tertiles of AIP (defined as 0.11, 0.11-0.21, > 0.21) based on their TG/HDL-C (AIP) levels.

resultsMean AIP of all patients undergoing CTO-PCI was 0.53 ± 0.29. The majority of patients were male (82.6%), and mean age was 61 ± 10.4 years. Increased AIP > 0.21 was associated with longer occlusion length (statistical trend p = 0.082) and stent routes (p = 0.022) and with a higher number of implanted stents (n > 4) (statistical trend p = 0.072). Success rates were similar in all AIP categories (p = 0.461). In-hospital PCI-related complications were rare and not statistically different (p = 0.852).

conclusionsThis study demonstrates for the first time that an increased AIP may predict the complexity of CTO-PCI and additionally may help to improve planning and quality of CTO-PCI.

Indexed as

Coronary OcclusionPercutaneous Coronary InterventionChronic DiseaseFemaleHumansMaleMiddle AgedRisk FactorsStentsTreatment Outcomeatherogenic indexchronic total occlusioncoronary artery diseasepercutaneous coronary intervention

Identifiers

PMID29924378
PMCPMC8079089
OpenAlexW2809663974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.