ArticleAnais brasileiros de dermatologia2018
Recurrent aphthous ulceration: an epidemiological study of etiological factors, treatment and differential diagnosis.
Article in Anais brasileiros de dermatologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Effectiveness of 0.1% triamcinolone acetonide compared with those of other therapies for minor recurrent aphthous stomatitis: a systematic review and meta-analysis of randomized controlled trials.BMC oral health · 2025Pooled it
- Topical Licorice for Aphthous: A Systematic Review of Clinical Trials.Iranian journal of medical sciences · 2023Pooled it
- Evaluation of the Effects of Punica granatum Flower Tablets on Pain and Healing of Minor Recurrent Aphthous Stomatitis: A Randomized Clinical Trial.Clinical and experimental dental research · 2024Trial
- Evaluation of the effect of probiotic lozenges in the treatment of recurrent aphthous stomatitis: a randomized, controlled clinical trial.Clinical oral investigations · 2021Trial
- Evaluation of zinc sulfate mucoadhesive formulation on recurrent aphthous stomatitis: a randomized double-blind, placebo-controlled clinical trial.BMC oral health · 2020Trial
- Prevalence profile perceived stress and impact on quality of life for recurrent aphthous ulcers: a cross-sectional epidemiological study in Egypt.BMC oral health · 2026Article
- Prevalence and Risk Factors of Aphthous Ulcers Following Periodontal Surgery: A Cross-Sectional Analysis.Journal of clinical medicine · 2026Article
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- Review on role of honey in disease prevention and treatment through modulation of biological activities.Open life sciences · 2025Review
- Assessment of Quality of Life in Patients with Chronic Oral Mucosal Diseases Using the Indonesian Version of the Chronic Oral Mucosal Disease Questionnaire-15 (COMDQ-15).Dentistry journal · 2024Article
- Optimization and preparation of a compound cod liver oil film former agent: an orthogonal design.Frontiers in pharmacology · 2024Article
- Deep learning algorithms for classification and detection of recurrent aphthous ulcerations using oral clinical photographic images.Journal of dental sciences · 2024Article
- The profile of Oral Health Branch of Rafsanjan Cohort Study (OHBRCS) in Rafsanjan City, southeast of Iran.Preventive medicine reports · 2023Article
- The Correlation Between IFNG Gene Methylation and Th1|Th2 Cell Balance in ROU and the Interventional Study of Jiaweidaochi Powder.Applied biochemistry and biotechnology · 2023Article
- Management of Recurrent Aphthous Stomatitis: An Indian Expert Consensus.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
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- Healing of Recurrent Aphthous Stomatitis by Non-Thermal Plasma: Pilot Study.Biomedicines · 2023Article
- Prevalence and risk factors of recurrent aphthous stomatitis among college students at Mangalore, India.PeerJ · 2023Article
- Efficacy of Topical Intervention for Recurrent Aphthous Stomatitis: A Network Meta-Analysis.Medicina (Kaunas, Lithuania) · 2022Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecurrent aphthous ulcerations are common benign ulcerated lesions on the mouth, whose etiology is poorly understood, with controversial treatment and difficult to control in clinical practice.
objectiveTo evaluate the cases of recurrent aphthous ulcerations with a focus on treatment, diagnosis and etiology.
methodsThis is a retrospective study of the cases of the Oral Diagnosis service of the Rio Grande do Norte Federal University in Natal/RN. Data such as sex, age, race, location, smoking habits, types of treatment, relapsing episodes, laboratory test results and clinical characteristics were collected. The associations between the variables were analyzed using the Pearson Chi-square test (p <0.05).
resultsA total of 4895 patients were seen in the service over a period of 11 years. Of these, 161 (3.3%) had complaints of oral aphthous ulcerations, of which 76 (47.2%) were diagnosed as suffering from recurrent aphthous ulcerations and 68 (42.2%) with clinical information necessary for evaluation. The tongue was the most affected anatomical region, with 27 individuals (39.7%), followed by the buccal mucosa, with 22 cases (32.3%). STUDY LIMITATIONS: Retrospective study with data from medical records.
conclusionDental surgeons, dermatologists and otorhinolaryngologists are the main responsible for the first contact with patients with this disease and should be attentive to the clinical aspects and treat each patient in an individualized way, since the therapy is palliative, its diagnosis is by exclusion and its etiology is unknown.
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