ReviewAnais brasileiros de dermatologia2018
Tuberous sclerosis complex: review based on new diagnostic criteria.
Review in Anais brasileiros de dermatologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it, 146 citations in OpenAlex.
- Everolimus as a therapeutic option in refractory epilepsy in children with tuberous sclerosis: a systematic review.Arquivos de neuro-psiquiatria · 2023Pooled it
- Delayed Diagnosis of Tuberous Sclerosis Complex Presenting as Abnormal Uterine Bleeding: A Case Report and Literature Review.Clinical case reports · 2026Article
- A case report of transcatheter arterial embolization for extra-renal retroperitoneal angiomyolipoma associated with tuberous sclerosis complex.Radiology case reports · 2026Article
- Spontaneous rupture of renal angiomyolipoma with characteristic skin findings.JAAD case reports · 2026Article
- Delayed TSC Diagnosis Presenting as End-Stage Renal Disease With Renal and Hepatic Angiomyolipoma: Case Report and Review.Clinical case reports · 2025Article
- Renal Cell Carcinoma in a Girl With Tuberous Sclerosis Due to a New Mutation.Journal of medical cases · 2025Article
- Cutaneous manifestations-associated with tuberous sclerosis complex and the use of topical rapamycin in the United States: a sub-analysis of an international survey of caregivers and patients.Orphanet journal of rare diseases · 2025Article
- Congenital and Neonatal Skin Disorders: Histopathological Diagnosis and Syndromic Associations.Cureus · 2025Review
- A diagnostic approach to neurocutaneous syndromes.Arquivos de neuro-psiquiatria · 2025Review
- Genetic syndromes associated with pancreatic neuroendocrine neoplasms and imaging diagnostic strategies.Abdominal radiology (New York) · 2025Review
- The role and mechanism of TSC in kidney diseases: a literature review.BMC nephrology · 2025Review
- Narrative Review on Common Traits of Parkinson's Disease and Epilepsy.Journal of clinical medicine · 2025Review
- Foetal cardiac rhabdomyoma due to paternalPathologica · 2025Review
- Giant renal angiomyolipoma unmasks underlying lymphangioleiomyomatosis: a case report and literature review.Frontiers in medicine · 2025Article
- APakistan journal of medical sciences · 2025Article
- Everolimus on cystic kidney disease burden reduction in pediatric tuberous sclerosis complex patients: a case series.BMC nephrology · 2024Article
- Renal Angiomyolipoma with Tumor Thrombus in the Inferior Vena Cava and Right Atrium Accompanied by Renal Cell Carcinoma: A Case Report.Medicina (Kaunas, Lithuania) · 2024Article
- Challenges of siblings with tuberous sclerosis showing various manifestations and severe complications.Radiology case reports · 2024Article
- Identification of a complex intrachromosomal inverted insertion in the long arm of chromosome 9 as a cause of tuberous sclerosis complex in a Korean family.Molecular genetics & genomic medicine · 2024Article
- Unusual adult-onset cardiac rhabdomyomas in tuberous sclerosis complex: a case report.Frontiers in medicine · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberous sclerosis complex is a multisystemic, autosomal dominant genetic disorder with complete penetrance, that can evolve with hamartomas in multiple organs, such as skin, central nervous system, kidney and lung. Due to the wide phenotypic variability, the disease is often not recognized. Tuberous sclerosis complex affects one in 10,000 newborns and most patients are diagnosed during the first 15 months of life. The diagnostic criteria for tuberous sclerosis were reviewed in 2012, at the second International Tuberous Sclerosis Complex Consensus Conference. The diagnosis is based on genetic criteria, by the identification of inactivating pathogenic mutation of tumor suppressor genes TSC1 and TSC2, and clinical criteria, including cutaneous, renal, pulmonary, cardiac and neurological manifestations. The treatment of tuberous sclerosis complex consists, mainly, in management of the symptoms caused by hamartomas and in prevention of organ failure. Multidisciplinary approach is recommended, in order to obtain better clinical outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.