ArticleEpidemiology and infection2018
Delay from symptom onset to treatment start among tuberculosis patients in England, 2012-2015.
Article in Epidemiology and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Concurrent Rasmussen aneurysm and pulmonary embolism in a patient with cavitary pulmonary tuberculosis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Article
- Exposures associated with tuberculosis presentation and healthcare delays in South West England, 2015-2020.PloS one · 2026Article
- A rapid review of the causes of diagnostic and treatment delays for tuberculosis in low-burden countries.Journal of public health (Oxford, England) · 2025Review
- Article
- Assessing heterogeneity of patient and health system delay among TB in a population with internal migrants in China.Frontiers in public health · 2024Article
- Article
- A clinically-guided unsupervised clustering approach to recommend symptoms of disease associated with diagnostic opportunities.Diagnosis (Berlin, Germany) · 2023Article
- A temporal analysis on patient and health service delays in pulmonary tuberculosis in Portugal: inter and intra‑regional differences and in(equalities) between gender and age.BMC public health · 2022Article
- Magnitude and determinants of delay in diagnosis of tuberculosis patients in Ethiopia: a systematic review and meta-analysis: 2020.Archives of public health = Archives belges de sante publique · 2022Article
- Delayed diagnosis of active pulmonary tuberculosis - potential risk factors for patient and healthcare delays in Portugal.BMC public health · 2021Article
- Article
- Factors Associated With the Presence of Tuberculous Empyema in Children With Pleural Tuberculosis.Frontiers in pediatrics · 2021Article
- Treatment delay in childhood pleural tuberculosis and associated factors.BMC infectious diseases · 2020Article
- Determination of related factors about diagnostic and treatment delays in patients with smear-positive pulmonary tuberculosis in TurkeyTurkish journal of medical sciences · 2020Article
- Factors associated with delay in treatment initiation for pulmonary tuberculosis.ERJ open research · 2020Article
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Authors and funding
6 authors.
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Abstract
Improving access to tuberculosis (TB) care and ensuring early diagnosis are two major aims of the WHO End TB strategy and the Collaborative TB Strategy for England. This study describes risk factors associated with diagnostic delay among TB cases in England. We conducted a retrospective cohort study of TB cases notified to the Enhanced TB Surveillance System in England between 2012 and 2015. Diagnostic delay was defined as more than 4 months between symptom onset and treatment start date. Multivariable logistic regression was used to identify demographic and clinical factors associated with diagnostic delay. Between 2012 and 2015, 22 422 TB cases were notified in England and included in the study. A third (7612) of TB cases had a diagnostic delay of more than 4 months. Being female, aged 45 years and older, residing outside of London and having extra-pulmonary TB disease were significantly associated with a diagnostic delay in the multivariable model (aOR = 1.2, 1.2, 1.2, 1.3, 1.8, respectively). This study identifies demographic and clinical factors associated with diagnostic delay, which will inform targeted interventions to improve access to care and early diagnosis among these groups, with the ultimate aim of helping reduce transmission and improve treatment outcomes for TB cases in England.
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