ReviewAmerican journal of primatology2018
Bridging the gap between rodents and humans: The role of non-human primates in oxytocin research.
Review in American journal of primatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Article
- Primate preoptic neurons drive hypothermia and cold defense.Innovation (Cambridge (Mass.)) · 2023Article
- Oxytocin receptors are widely distributed in the prairie vole (Microtus ochrogaster) brain: Relation to social behavior, genetic polymorphisms, and the dopamine system.The Journal of comparative neurology · 2022Article
- Oxytocin does not stand alone.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Interplay between the oxytocin and opioid systems in regulating social behaviour.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Exploring gene-culture coevolution in humans by inferring neuroendophenotypes: A case study of the oxytocin receptor gene and cultural tightness.Genes, brain, and behavior · 2022Article
- The neural circuits of monogamous behavior.Frontiers in neural circuits · 2022Review
- LC-MS/MS measurement of endogenous oxytocin in the posterior pituitary and CSF of macaques: A pilot study.Peptides · 2021Article
- Oxytocin promotes prosocial behavior and related neural responses in infant macaques at-risk for compromised social development.Developmental cognitive neuroscience · 2021Article
- Neural correlates of mating system diversity: oxytocin and vasopressin receptor distributions in monogamous and non-monogamous Eulemur.Scientific reports · 2021Article
- Neuronal Circuits for Social Decision-Making and Their Clinical Implications.Frontiers in neuroscience · 2021Review
- Examining Empathy Through Consolation Behavior in Prairie Voles.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2021Article
- Prefrontal-amygdala circuits in social decision-making.Nature neuroscience · 2021Review
- Methylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques.Hormones and behavior · 2020Article
- Circuits for social learning: A unified model and application to Autism Spectrum Disorder.Neuroscience and biobehavioral reviews · 2019Review
- Effect of age and autism spectrum disorder on oxytocin receptor density in the human basal forebrain and midbrain.Translational psychiatry · 2018Article
- Oxytocin- and arginine vasopressin-containing fibers in the cortex of humans, chimpanzees, and rhesus macaques.American journal of primatology · 2018Article
- Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Oxytocin (OT), a neuropeptide that acts in the brain as a neuromodulator, has been long known to shape maternal physiology and behavior in mammals, however its role in regulating social cognition and behavior in primates has come to the forefront only in the recent decade. Many of the current perspectives on the role of OT in modulating social behavior emerged first from studies in rodents, where invasive techniques with a high degree of precision have permitted the mechanistic dissection of OT-related behaviors, as well as their underlying neural circuits in exquisite detail. In parallel, behavioral and imaging studies in humans have suggested that brain OT may similarly influence human social behavior and neural activity. These studies in rodents and humans have spurred interest in the therapeutic potential of targeting the OT system to remedy deficits in social cognition and behavior that are present across numerous psychiatric disorders. Yet there remains a tremendous gap in our mechanistic understanding of the influence of brain OT on social neural circuitry between rodents and man. In fact, very little is known regarding the neural mechanisms by which exogenous or endogenous OT influences human social cognition, limiting its therapeutic potential. Here we discuss how non-human primates (NHPs) are uniquely positioned to now bridge the gaps in knowledge provided by the precise circuit-level approaches widely used in rodent models and the behavioral, imaging, and clinical studies in humans. This review provides a perspective on what has been achieved, and what can be expected from exploring the role of OT in shaping social behaviors in NHPs in the coming years.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.