ReviewEnvironmental science and pollution research international2018
Organic micropollutants paracetamol and ibuprofen-toxicity, biodegradation, and genetic background of their utilization by bacteria.
Review in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
60 citing papers in PubMed.
- Effects of environmentally relevant ibuprofen and valproic acid exposure on zebrafish behavior.Biomolecules & biomedicine · 2026Article
- Facile synthesis of BiRSC advances · 2026Article
- Microbial degradation of acetaminophen, a pharmaceutical compound, using the ascomycete fungus Trichoderma asperellum.Folia microbiologica · 2026Article
- Advanced microbial engineering approaches for biodegradation of pharmaceutical pollutants.Biodegradation · 2025Review
- Removal of Ibuprofen from Contaminated Water by Bioaugmentation with Novel Bacterial Strains Isolated from Sewage Sludge.Microorganisms · 2025Article
- Uptake, Partitioning, and Accumulation of High and Low Rates of Carbamazepine in Hydroponically Grown Lettuce (Plants (Basel, Switzerland) · 2025Article
- Greywater Reuse: Contaminant Profile, Health Implications, and Sustainable Solutions.International journal of environmental research and public health · 2025Review
- Article
- Bioremediation of Synthetic Wastewater with Contaminants of Emerging Concern byBioengineering (Basel, Switzerland) · 2025Article
- Genetic and species rearrangements in microbial consortia impact biodegradation potential.The ISME journal · 2025Article
- Microbes as Resources to Remove PPCPs and Improve Water Quality.Microbial biotechnology · 2025Review
- Removal of Ibuprofen in Water by Bioaugmentation withJournal of xenobiotics · 2024Article
- Pharmaceuticals removal from hospital wastewater by fluidized aerobic bioreactor in combination with tubesettler.Scientific reports · 2024Article
- Article
- Performance evaluation of a new sponge-based moving bed biofilm reactor for the removal of pharmaceutical pollutants from real wastewater.Scientific reports · 2024Article
- Article
- Synergistic effect of ZnO/AgHeliyon · 2024Article
- Non-antibiotic pharmaceuticals are toxic against Escherichia coli with no evolution of cross-resistance to antibiotics.npj antimicrobials and resistance · 2024Article
- Pollutant profile complexity governs wastewater removal of recalcitrant pharmaceuticals.The ISME journal · 2024Article
- Microbial degradation of contaminants of emerging concern: metabolic, genetic and omics insights for enhanced bioremediation.Frontiers in bioengineering and biotechnology · 2024Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Currently, analgesics and nonsteroidal anti-inflammatory drugs (NSAIDs) are classified as one of the most emerging group of xenobiotics and have been detected in various natural matrices. Among them, monocyclic paracetamol and ibuprofen, widely used to treat mild and moderate pain are the most popular. Since long-term adverse effects of these xenobiotics and their biological and pharmacokinetic activity especially at environmentally relevant concentrations are better understood, degradation of such contaminants has become a major concern. Moreover, to date, conventional wastewater treatment plants (WWTPs) are not fully adapted to remove that kind of micropollutants. Bioremediation processes, which utilize bacterial strains with increased degradation abilities, seem to be a promising alternative to the chemical methods used so far. Nevertheless, despite the wide prevalence of paracetamol and ibuprofen in the environment, toxicity and mechanism of their microbial degradation as well as genetic background of these processes remain not fully characterized. In this review, we described the current state of knowledge about toxicity and biodegradation mechanisms of paracetamol and ibuprofen and provided bioinformatics analysis concerning the genetic bases of these xenobiotics decomposition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.