Evidence map›Paper›PMID 29922932›Full record

ArticleEuropean radiology2019

Pre-TACE kurtosis of ADC

Li-Fang Wu, Sheng-Xiang Rao, Peng-Ju Xu, Li Yang, Cai-Zhong Chen, Hao Liu, Jian-Feng Huang, Cai-Xia Fu, Alice Halim, Meng-Su Zeng

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04299919 (The Artificial Intelligent Prognostic Assessment and Pathological Basis Research of Early Primary Hepatocellular Carcinoma After Minimally Invasive Treatment Based on Multimodal MRI and Clinical Big Data), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04299919 unknown statusnot on this map

The Artificial Intelligent Prognostic Assessment and Pathological Basis Research of Early Primary Hepatocellular Carcinoma After Minimally Invasive Treatment Based on Multimodal MRI and Clinical Big Data

TypeobservationalSponsorThe First Affiliated Hospital of Dalian Medical UniversityRan2007 to 2024Enrolled1,200ConditionsHepatocellular CarcinomaArmsMinimally invasive treatment, Hepatectomy
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

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  17. Radiomics of hepatocellular carcinoma.Abdominal radiology (New York) · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Li-Fang WuShanghai Institute of Medical Imaging, Department of Radiology, Zhongshan Hospital, Fudan University, No. 180, Fenglin Road, Xuhui District, Shanghai, 200032, China.
Sheng-Xiang RaoDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, No. 180, Fenglin Road, Xuhui District, Shanghai, 200032, China.
Peng-Ju XuDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, No. 180, Fenglin Road, Xuhui District, Shanghai, 200032, China.
Li YangDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, No. 180, Fenglin Road, Xuhui District, Shanghai, 200032, China.
Cai-Zhong ChenDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, No. 180, Fenglin Road, Xuhui District, Shanghai, 200032, China.
Hao LiuDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, No. 180, Fenglin Road, Xuhui District, Shanghai, 200032, China.
Jian-Feng HuangDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, No. 180, Fenglin Road, Xuhui District, Shanghai, 200032, China.
Cai-Xia FuSiemens Healthcare, Siemens MR Center, Gaoxin C. Ave., 2nd, Hi-Tech Industrial Park, Shenzhen, 518057, China.
Alice HalimFudan University, No. 130, Dongan Road, Xuhui District, Shanghai, 200032, China.
Meng-Su ZengDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, No. 180, Fenglin Road, Xuhui District, Shanghai, 200032, China. zeng.mengsu@zs-hospital.sh.cn.
The First Affiliated Hospital, Sun Yat-sen University · CNFudan University · CNSun Yat-sen University · CNZhongshan Hospital · CNSiemens (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the feasibility of pre-TACE IVIM imaging based on histogram analysis for predicting prognosis in the treatment of unresectable hepatocellular carcinoma (HCC). MATERIALS AND

methodsFifty-five patients prospectively underwent 1.5T MRI 1 week before TACE. Histogram metrics for IVIM parameters and ADCs maps between responders and non-responders with mRECIST assessment were compared. Kaplan-Meier, log-rank tests and Cox proportional hazard regression model were used to correlate variables with time to progression (TTP).

resultsMean (p = 0.022), median (p = 0.043), and 25

conclusionPre-TACE kurtosis of ADC KEY POINTS: • mRECIST was associated with TTP independently. • Lower kurtosis and higher mean for ADCs tend to have good response. • Pre-TACE kurtosis of ADC

Indexed as

AdultAgedAged, 80 and overCarcinoma, HepatocellularChemoembolization, TherapeuticDiffusion Magnetic Resonance ImagingDisease ProgressionFeasibility StudiesFemaleHumansLiver NeoplasmsMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesDiffusionHepatocellular carcinomaMagnetic resonance imagingPrognosisTherapy

Identifiers

PMID29922932
OpenAlexW2809624348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.