Evidence map›Paper›PMID 29922896›Full record

ArticleCancer causes & control : CCC2018

Mapping hot spots of breast cancer mortality in the United States: place matters for Blacks and Hispanics.

Justin Xavier Moore, Kendra J Royston, Marvin E Langston, Russell Griffin, Bertha Hidalgo, Henry E Wang, Graham Colditz, Tomi Akinyemiju

Abstract read
In one paragraph

Article in Cancer causes & control : CCC, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Effects of Post-diagnosis Recreational Aerobic Exercise among Breast Cancer Survivors: A Systematic Review/Meta-Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Pooled it
  2. Examining the Role of the Social Vulnerability Index in the Association between Race/Ethnicity and Breast Cancer Outcomes.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  3. Where Should the Cancer Control Interventions Target: A Geospatial Hotspot Analysis for Major Cancer Mortality 2018 to 2022 in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Justin Xavier MooreDepartments of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA. jxmoore@wustl.edu.ORCID http://orcid.org/0000-0002-5496-752X
Kendra J RoystonComprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Marvin E LangstonDivision of Public Health Sciences, Department of Surgery, Washington University in Saint Louis School of Medicine, St Louis, MO, USA.
Russell GriffinDepartments of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Bertha HidalgoDepartments of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Henry E WangDepartment of Emergency Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
Graham ColditzDivision of Public Health Sciences, Department of Surgery, Washington University in Saint Louis School of Medicine, St Louis, MO, USA.
Tomi AkinyemijuDepartments of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

TRAINING AND CAREER DEVELOPMENTU54CA118948 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI UPENDER MANNE · 2005 to 2026
$26.6M
Cancer Prevention & Control Training ProgramR25CA047888 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DEMARK-WAHNEFRIED, WENDY, MENESES, KAREN M · 1988 to 2016
$11.2M
Postdoctoral Training in Cancer Prevention and ControlT32CA190194 · NCI · WASHINGTON UNIVERSITY · PI GRAHAM A. COLDITZ, AIMEE S JAMES · 2014 to 2026
$4.7M
Risk Factors for Sepsis in the CommunityR01NR012726 · NINR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WANG, HENRY E. · 2011 to 2015
$2.6M
Epigenomics of Cardiometabolic Diseases in Mexican AmericansK01HL130609 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HIDALGO, BERTHA · 2016 to 2019
$568k
Foundation for Barnes-Jewish Hospital T32190194National Institute for Nursing Research R01-NR012726NCI NIH HHS R25 CA047888NCI NIH HHS R25 CA47888NCI NIH HHS T32 CA190194NCI NIH HHS U54 CA118948NHLBI NIH HHS K01 HL130609NINR NIH HHS R01 NR012726
6 · The paper itself

Abstract

purposeThe goals of this study were to identify geographic and racial/ethnic variation in breast cancer mortality, and evaluate whether observed geographic differences are explained by county-level characteristics.

methodsWe analyzed data on breast cancer deaths among women in 3,108 contiguous United States (US) counties from years 2000 through 2015. We applied novel geospatial methods and identified hot spot counties based on breast cancer mortality rates. We assessed differences in county-level characteristics between hot spot and other counties using Wilcoxon rank-sum test and Spearman correlation, and stratified all analysis by race/ethnicity.

resultsAmong all women, 80 of 3,108 (2.57%) contiguous US counties were deemed hot spots for breast cancer mortality with the majority located in the southern region of the US (72.50%, p value < 0.001). In race/ethnicity-specific analyses, 119 (3.83%) hot spot counties were identified for NH-Black women, with the majority being located in southern states (98.32%, p value < 0.001). Among Hispanic women, there were 83 (2.67%) hot spot counties and the majority was located in the southwest region of the US (southern = 61.45%, western = 33.73%, p value < 0.001). We did not observe definitive geographic patterns in breast cancer mortality for NH-White women. Hot spot counties were more likely to have residents with lower education, lower household income, higher unemployment rates, higher uninsured population, and higher proportion indicating cost as a barrier to medical care.

conclusionsWe observed geographic and racial/ethnic disparities in breast cancer mortality: NH-Black and Hispanic breast cancer deaths were more concentrated in southern, lower SES counties.

Indexed as

Black or African AmericanBreast NeoplasmsFemaleHispanic or LatinoHumansUnited StatesBreast cancerGeospatial analysisHealth disparitiesSocioeconomic factors

Identifiers

PMID29922896
PMCPMC6301114

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.