Evidence map›Paper›PMID 29922649›Full record

ArticleFrontiers in cell and developmental biology2018

Post-transcriptional Modulation of Sphingosine-1-Phosphate Receptor 1 by miR-19a Affects Cardiovascular Development in Zebrafish.

Elena Guzzolino, Elena Chiavacci, Neha Ahuja, Laura Mariani, Monica Evangelista, Chiara Ippolito, Milena Rizzo, Deborah Garrity, Federico Cremisi, Letizia Pitto

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Dysregulated micro-RNAs and long noncoding RNAs in cardiac development and pediatric heart failure.American journal of physiology. Heart and circulatory physiology · 2020
    Review
  7. Sphingolipids in the Heart: From Cradle to Grave.Frontiers in endocrinology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Elena GuzzolinoInstitute of Clinical Physiology, National Research Council, Pisa, Italy.
Elena ChiavacciInstitute of Clinical Physiology, National Research Council, Pisa, Italy.
Neha AhujaDepartment of Biology, Center for Cardiovascular Research, Colorado State University, Fort Collins, CO, United States.
Laura MarianiInstitute of Clinical Physiology, National Research Council, Pisa, Italy.
Monica EvangelistaInstitute of Clinical Physiology, National Research Council, Pisa, Italy.
Chiara IppolitoDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Milena RizzoTumour Institute of Tuscany, Florence, Italy.
Deborah GarrityDepartment of Biology, Center for Cardiovascular Research, Colorado State University, Fort Collins, CO, United States.
Federico CremisiScuola Normale Superiore di Pisa, Pisa, Italy.
Letizia PittoInstitute of Clinical Physiology, National Research Council, Pisa, Italy.
Istituto di Fisiologia Clinica · ITColorado State University · USNational Research Council · ITScuola Normale Superiore · ITTumour Institute of Tuscany · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sphingosine-1-phosphate is a bioactive lipid and a signaling molecule integrated into many physiological systems such as differentiation, proliferation and migration. In mammals S1P acts through binding to a family of five trans-membrane, G-protein coupled receptors (S1PRs) whose complex role has not been completely elucidated. In this study we use zebrafish, in which seven

Indexed as

cardiovascular developmentHolt Oram syndromemicroRNAsphingosine-1-phosphate receptor 1zebrafish

Identifiers

PMID29922649
PMCPMC5996577
OpenAlexW2803836001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.