Evidence map›Paper›PMID 29922599›Full record

ArticleFrontiers in cellular and infection microbiology2018

César Díaz-Godínez, Zayda Fonseca, Mario Néquiz, Juan P Laclette, Carlos Rosales, Julio C Carrero

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Animals : an open access journal from MDPI · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Sepsis-induced NET formation requires MYD88 but is independent of GSDMD and PAD4.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  10. Neutrophil extracellular traps in homeostasis and disease.Signal transduction and targeted therapy · 2024
    Review
  11. Review
  12. Frontiers in immunology · 2024
    Article
  13. Review
  14. Review
  15. NETosis in Parasitic Infections: A Puzzle That Remains Unsolved.International journal of molecular sciences · 2023
    Review
  16. Review
  17. Review
  18. Molecular interplays of theFrontiers in cellular and infection microbiology · 2022
    Review
  19. Review
  20. Immunomodulatory effect of extracellular vesicles fromFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

César Díaz-GodínezLaboratory of Immunology, Department of Immunology, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Zayda FonsecaLaboratory of Immunology, Department of Immunology, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Mario NéquizLaboratory of Immunopathology, Department of Experimental Medicine, Hospital General de México, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Juan P LacletteLaboratory of Immunology, Department of Immunology, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Carlos RosalesLaboratory of Immunology, Department of Immunology, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Julio C CarreroLaboratory of Immunology, Department of Immunology, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Universidad Nacional Autónoma de México · MXHospital General de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophil extracellular traps (NETs) are DNA fibers decorated with histones and antimicrobial proteins from cytoplasmic granules released into the extracellular space in a process denominated NETosis. The molecular pathways involved in NETosis have not been completely understood. Classical NETosis mechanisms involve the neutrophil elastase (NE) translocation to nucleus due to the generation of reactive oxygen species (ROS) by NADPH oxidase (NOX2) or the peptidyl arginine deiminase 4 (PAD4) activation in response to an increase in extracellular calcium influx; both mechanisms result in DNA decondensation. Previously, we reported that trophozoites and lipopeptidophosphoglycan from

Indexed as

AcetophenonesApoptosisCalciumDNADNA, MitochondrialEntamoeba histolyticaEntamoebiasisExtracellular TrapsHumansLeukocyte ElastaseMicrobial ViabilityMitochondriaNADPH OxidasesNecrosisNeutrophilsOxidation-ReductionAcetophenonesacetovanilloneCalciumDNADNA, MitochondrialLeukocyte ElastaselipopeptidophosphoglycanNADPH OxidasesPADI4 protein, humanPeptidoglycanPhospholipidsProtein-Arginine DeiminasesProtein-Arginine Deiminase Type 4Reactive Oxygen SpeciesSerine Proteinase InhibitorsEntamoeba HistolyticaNETosisNETsneutrophilsNOX2PAD4ROS

Identifiers

PMID29922599
PMCPMC5996068
OpenAlexW2806454899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.