ReviewFrontiers in psychiatry2018
Neural Correlates for Intrinsic Motivational Deficits of Schizophrenia; Implications for Therapeutics of Cognitive Impairment.
Review in Frontiers in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Abnormal prediction error processing in schizophrenia and depression.Human brain mapping · 2021Pooled it
- Repurposing Caffeine, Metformin, and Furosemide to Target Schizophrenia-Related Impairments in a Triple-Hit Rat Model.International journal of molecular sciences · 2025Article
- Impact of negative symptom reduction on employment and vocational activity outcomes following cognitive remediation therapy in schizophrenia: A 1-year follow-up study.PCN reports : psychiatry and clinical neurosciences · 2025Article
- Evaluation of a new intrinsic and extrinsic motivation scale in youth with psychosis spectrum symptoms.Comprehensive psychiatry · 2023Article
- The thermodynamic brain and the evolution of intellect: the role of mental energy.Cognitive neurodynamics · 2020Review
- Brain morphological and functional features in cognitive subgroups of schizophrenia.Psychiatry and clinical neurosciences · 2020Article
- Targeting Cognition and Motivation in Coordinated Specialty Care for Early Psychosis: A Grant Report.Journal of psychiatry and brain science · 2020Article
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7 authors.
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Abstract
The ultimate goal of the treatment of schizophrenia is recovery, a notion related to improvement of cognitive and social functioning. Cognitive remediation therapies (CRT), one of the most effective cognition enhancing methods, have been shown to moderately improve social functioning. For this purpose, intrinsic motivation, related to internal values such as interest and enjoyment, has been shown to play a key role. Although the impairment of intrinsic motivation is one of the characteristics of schizophrenia, its neural mechanisms remain unclear. This is related to the lack of feasible measures of intrinsic motivation, and its response to treatment. According to the self-determination theory (SDT), not only intrinsic motivation, but extrinsic motivation has been reported to enhance learning and memory in healthy subjects to some extent. This finding suggests the contribution of different types of motivation to potentiate the ability of the CRT to treat cognitive impairment of schizophrenia. In this paper, we provide a review of psychological characteristics, assessment methods, and neural correlates of intrinsic motivation in healthy subjects and patients with schizophrenia. Particularly, we focus on neuroimaging studies of intrinsic motivation, including our own. These considerations are relevant to enhancement of functional outcomes of schizophrenia.
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