Evidence map›Paper›PMID 29922180›Full record

ArticleFrontiers in physiology2018

Increased Reactive Oxygen Species and Cell Cycle Defects Contribute to Anemia in the RASA3 Mutant Mouse Model s

Emily S Hartman, Elena C Brindley, Julien Papoin, Steven L Ciciotte, Yue Zhao, Luanne L Peters, Lionel Blanc

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Acta pharmaceutica Sinica. B · 2022
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Emily S HartmanLaboratory of Developmental Erythropoiesis, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, The Feinstein Institute for Medical Research, Manhasset, NY, United States.
Elena C BrindleyLaboratory of Developmental Erythropoiesis, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, The Feinstein Institute for Medical Research, Manhasset, NY, United States.
Julien PapoinLaboratory of Developmental Erythropoiesis, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, The Feinstein Institute for Medical Research, Manhasset, NY, United States.
Steven L CiciotteThe Jackson Laboratory, Bar Harbor, ME, United States.
Yue ZhaoThe Jackson Laboratory, Bar Harbor, ME, United States.
Luanne L PetersThe Jackson Laboratory, Bar Harbor, ME, United States.
Lionel BlancLaboratory of Developmental Erythropoiesis, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, The Feinstein Institute for Medical Research, Manhasset, NY, United States.
Feinstein Institute for Medical Research · USJackson Laboratory · US

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
Critical Regulatory Circuits in Blood FormationR01HL134043 · NHLBI · JACKSON LABORATORY · PI PETERS, LUANNE L · 2016 to 2019
$2.6M
NCI NIH HHS P30 CA034196NHLBI NIH HHS R01 HL134043
6 · The paper itself

Abstract

RASA3 is a Ras GTPase activating protein that plays a critical role in blood formation. The autosomal recessive mouse model

Indexed as

anemiaaplasticapoptosisbone marrow failure syndromescell cycleerythropoiesismouse modelsreactive oxygen species (ROS)

Identifiers

PMID29922180
PMCPMC5996270
OpenAlexW2803401645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.