Evidence map›Paper›PMID 29922040›Full record

ArticleDrug design, development and therapy2018

Burden of heart failure on patients from China: results from a cross-sectional survey.

James Ds Jackson, Sarah E Cotton, Sara Bruce Wirta, Catia C Proenca, Milun Zhang, Raquel Lahoz, Frederico J Calado

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. TraditionalFrontiers in cardiovascular medicine · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Psychometric Validation of the Living with Chronic Illness Scale in Patients with Chronic Heart Failure.International journal of environmental research and public health · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Effect of health literacy on quality of life among patients with chronic heart failure in China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

James Ds JacksonReal World Research, Adelphi Real World, Bollington, UK.
Sarah E CottonReal World Research, Adelphi Real World, Bollington, UK.
Sara Bruce WirtaReal World Evidence, Cardio-Metabolics Franchise, Novartis Sweden AB, Stockholm, Sweden.
Catia C ProencaWellmera AG, Basel, Switzerland.
Milun ZhangHealth Economics and Outcomes Research and Access Strategy, Novartis Pharma China, Beijing, China.
Raquel LahozReal World Evidence, Cardio-Metabolics Franchise, Novartis Pharma AG, Basel, Switzerland.
Frederico J CaladoReal World Evidence, Cardio-Metabolics Franchise, Novartis Pharma AG, Basel, Switzerland.
Adelphi Group (United Kingdom) · GBNovartis (Switzerland) · CHNovartis (China) · CNNovartis (Sweden) · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLittle evidence exists on the burden that chronic heart failure (HF) poses specifically to patients in China. The objective of this study, therefore, was to describe the burden of HF on patients in China. MATERIALS AND

methodsA cross-sectional survey of cardiologists and their patients with HF was conducted. Patient record forms were completed by 150 cardiologists for 10 consecutive patients. Patients for whom a patient record form was completed were invited to complete a patient questionnaire.

resultsMost of the 933 patients (mean [SD] age 65.8 [10.2] years; 55% male; 80% retired) included in the study received care in tier 2 and 3 hospitals in large cities. Patients gave a median score of 4 on a scale from 1 (no disruption) to 10 (severe disruption) to describe how much HF disrupts their everyday life. Patients in paid employment (8%) missed 10% of work time and experienced 29% impairment in their ability to work due to HF in the previous week. All aspects of patients' health-related quality of life (QoL) were negatively affected by their condition. Mean ± SD utility calculated by the 3-level 5-dimension EuroQol questionnaire was 0.8±0.2, and patients rated their health at 70.3 (11.5) on a 100 mm visual analog scale. Patients incurred costs associated with HF treatment, travel, and professional caregiving services.

conclusionHF is associated with poor health-related QoL and considerable disruption in patients' lives. Novel and improved therapies are needed to reduce the burden of HF on patients and the health care system.

Indexed as

Cost of IllnessAgedCaregiversChinaCross-Sectional StudiesEmploymentFemaleHeart FailureHumansMaleMiddle AgedQuality of Lifehealth-related quality of lifeheart failurepatient burdenreal-worldsurvey

Identifiers

PMID29922040
PMCPMC5996854
OpenAlexW2807275622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.