Evidence map›Paper›PMID 29921768›Full record

ArticleMolecules (Basel, Switzerland)2018

Compound K Induces Endoplasmic Reticulum Stress and Apoptosis in Human Liver Cancer Cells by Regulating STAT3.

Xuan Zhang, Silin Zhang, Qitong Sun, Wenjun Jiao, Yan Yan, Xuewu Zhang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
  2. Research Progress on the Anticancer Effect of Ginsenoside Rh1.Current issues in molecular biology · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. 20(Journal of ginseng research · 2021
    Article
  19. Anticancer Activities of Ginsenosides, the Main Active Components of Ginseng.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xuan ZhangCollege of Medicine, Yanbian University, Yanji 133000, China. zxfly1028@163.com.
Silin ZhangCollege of Medicine, Yanbian University, Yanji 133000, China. zhangchuchu1103@163.com.
Qitong SunCollege of Medicine, Yanbian University, Yanji 133000, China. single0124@163.com.
Wenjun JiaoCollege of Medicine, Yanbian University, Yanji 133000, China. jwj0237@163.com.
Yan YanCollege of Medicine, Yanbian University, Yanji 133000, China. 18243392601@163.com.
Xuewu ZhangCollege of Medicine, Yanbian University, Yanji 133000, China. zhangxuewu@ybu.edu.cn.
Yanbian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ginsenoside compound K (20-

Indexed as

AnimalsApoptosisCarcinoma, HepatocellularEndoplasmic Reticulum Chaperone BiPEndoplasmic Reticulum StressFemaleGinsenosidesHep G2 CellsHumansLiver NeoplasmsMiceMice, Inbred BALB CMice, NudeNeoplasm ProteinsSTAT3 Transcription FactorXenograft Model Antitumor AssaysEndoplasmic Reticulum Chaperone BiPGinsenosidesHSPA5 protein, humanHspa5 protein, mouseNeoplasm ProteinsSTAT3 protein, humanSTAT3 Transcription FactorapoptosisCKERSginsenosidehepatomaSTAT3

Identifiers

PMID29921768
PMCPMC6099685
OpenAlexW2808965798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.