ArticleOccupational and environmental medicine2018
Night work and prostate cancer risk: results from the EPICAP Study.
Article in Occupational and environmental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Chronotype differences in the risk of cancers, diabetes mellitus, and poor mental health among shift workers: a meta-analysis.Scandinavian journal of work, environment & health · 2026Pooled it
- Nightshift work and risk of breast and prostate cancer: a systematic review and meta-analysis, 2012-2023.Anales del sistema sanitario de Navarra · 2025Pooled it
- Shift Work and Prostate Cancer: An Updated Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Association Between Night-Shift Work and Cancer Risk: Updated Systematic Review and Meta-Analysis.Frontiers in oncology · 2020Pooled it
- Sleep Duration and Prostate Cancer Risk in the Southern Community Cohort Study.Cancer medicine · 2026Article
- Firefighting, other protective service occupations and prostate cancer risk: a pooled analysis of three case-control studies.Journal of occupational medicine and toxicology (London, England) · 2025Article
- Night shift work and prostate cancer: a large cohort study from UK Biobank and Mendelian randomisation study.BMJ open · 2024Article
- Circadian rhythm disruption and endocrine-related tumors.World journal of clinical oncology · 2024Review
- Article
- A review for the impacts of circadian disturbance on urological cancers.Sleep and biological rhythms · 2024Review
- Co-delivery of Siape1 and Melatonin byRecent patents on anti-cancer drug discovery · 2024Article
- Association between Outdoor Light at Night and Prostate Cancer in the Health Professionals Follow-up Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- Unmasking the Hidden Danger: A Decade-Long Systematic Review of Case-Control Studies on Single Occupational Risks and Prostate Cancer.Life (Basel, Switzerland) · 2023Review
- Night shift work and risk of aggressive prostate cancer in the Norwegian Offshore Petroleum Workers (NOPW) cohort.International journal of epidemiology · 2023Article
- Review
- The association between night shift work and breast cancer risk in the Finnish twins cohort.European journal of epidemiology · 2023Article
- Prostate cancer in workers exposed to night-shift work: two cases recognized by the Korean Epidemiologic Investigation Evaluation Committee.Annals of occupational and environmental medicine · 2023Article
- Circadian clocks in health and disease: Dissecting the roles of the biological pacemaker in cancer.F1000Research · 2023Review
- Circadian Clock Dysregulation and Prostate Cancer: A Molecular and Clinical Overview.Clinical Medicine Insights. Oncology · 2023Review
- Occupation and prostate Cancer risk: results from the epidemiological study of prostate cancer (EPICAP).Journal of occupational medicine and toxicology (London, England) · 2022Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the role of night work in prostate cancer based on data from the EPICAP Study.
methodsEPICAP is a French population-based case-control study including 818 incident prostate cancer cases and 875 frequency-matched controls that have been interviewed face to face on several potential risk factors including lifetime occupational history. Detailed information on work schedules for each job (permanent or rotating night work, duration, total number of nights, length of the shift, number of consecutive nights) as well as sleep duration and chronotype, was gathered. Prostate cancer aggressiveness was assessed by Gleason Score.
resultsNight work was not associated with prostate cancer, whatever the aggressiveness of prostate cancer, while we observed an overall increased risk among men with an evening chronotype (OR=1.83, 95% CI 1.05 to 3.19). A long duration of at least 20 years of permanent night work was associated with aggressive prostate cancer (OR=1.76, 95% CI 1.13 to 2.75), even more pronounced in combination with a shift length >10 hours or ≥ 6 consecutive nights (OR=4.64, 95% CI 1.78 to 12.13; OR=2.43, 95% CI 1.32 to 4.47, respectively).
conclusionOverall, ever night work, either permanent or rotating, was not associated to prostate cancer. Nevertheless, our results suggest that a long duration of permanent night work in combination with a long shift length or at least six consecutive nights may be associated with prostate cancer, particularly with aggressive prostate cancer. Further studies are needed to confirm those findings.
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