The rs3850641 polymorphism of the TNFSF4 gene increases the risk of myocardial infarction in a Chinese Han population.

Changqing Lu, Helei Jia, Aiguo Xu

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Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.3field-weighted citation impact, top 38% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Changqing LuDepartment of Emergency, The Second Affiliated Hospital of Henan University of Chinese Medicine (Henan Province Hospital of Traditional Chinese Medicine), Zhengzhou, Henan 450002, China.

Helei JiaDepartment of Emergency, Henan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan 450002, China.

Aiguo XuRespiratory Intensive Care Unit, The First Affiliated Hospital Zhengzhou University, Zhengzhou 450052, China xvaiguo@sohu.com.

First Affiliated Hospital of Zhengzhou University · CNHenan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor necrosis factor superfamily member 4 (TNFSF4), also known as Ox40 ligand (Ox40l), plays an important role in atherosclerosis development. Several studies reported the association between the rs3850641 polymorphism of the TNFSF4 gene and the risk of myocardial infarction (MI). However, the results are inconsistent. In order to explore the relationship between the rs3850641 polymorphism of the TNFSF4 gene and MI, we conducted a case-control study including 454 cases and 512 controls in a Chinese Han population. Genotyping was performed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. The present study found that AA genotype (AA vs. GG: odds ratio (OR) & 95% confidence interval (CI), 2.00(1.04,3.86),

Indexed as

Polymorphism, Single NucleotideAgedAsian PeopleCase-Control StudiesChinaFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedMyocardial InfarctionOdds RatioOX40 LigandRisk FactorsOX40 LigandTNFSF4 protein, humancase-control studymyocardial infarctionsingle-nucleotide polymorphismTNFSF4

Identifiers

PMID29921578

DOI10.1042/BSR20180526

PMCPMC6043721

OpenAlexW2809010514

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.