Evidence map›Paper›PMID 29921324›Full record

ArticleBMC research notes2018

Mitochondrial genome variation of Atlantic cod.

Tor Erik Jørgensen, Bård Ove Karlsen, Åse Emblem, Ragna Breines, Morten Andreassen, Trine B Rounge, Alexander J Nederbragt, Kjetill S Jakobsen, Marianne Nymark, Anita Ursvik and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Tor Erik JørgensenGenomics Group, Faculty of Biosciences and Aquaculture, Nord University, 8049, Bodø, Norway.
Bård Ove KarlsenResearch Laboratory and Department of Laboratory Medicine, Nordland Hospital, Bodø, Norway.
Åse EmblemDepartment of Medical Biology, Faculty of Health Sciences, UiT-Arctic University of Norway, Tromsø, Norway.
Ragna BreinesDepartment of Medical Biology, Faculty of Health Sciences, UiT-Arctic University of Norway, Tromsø, Norway.
Morten AndreassenDepartment of Medical Biology, Faculty of Health Sciences, UiT-Arctic University of Norway, Tromsø, Norway.
Trine B RoungeCentre for Ecological and Evolutionary Syntheses (CEES), Department of Biosciences, University of Oslo, Oslo, Norway.
Alexander J NederbragtCentre for Ecological and Evolutionary Syntheses (CEES), Department of Biosciences, University of Oslo, Oslo, Norway.
Kjetill S JakobsenCentre for Ecological and Evolutionary Syntheses (CEES), Department of Biosciences, University of Oslo, Oslo, Norway.
Marianne NymarkDepartment of Medical Biology, Faculty of Health Sciences, UiT-Arctic University of Norway, Tromsø, Norway.
Anita UrsvikDepartment of Medical Biology, Faculty of Health Sciences, UiT-Arctic University of Norway, Tromsø, Norway.
Dag H CoucheronDepartment of Medical Biology, Faculty of Health Sciences, UiT-Arctic University of Norway, Tromsø, Norway.
Lars Martin JaktGenomics Group, Faculty of Biosciences and Aquaculture, Nord University, 8049, Bodø, Norway.
Jarle T NordeideGenomics Group, Faculty of Biosciences and Aquaculture, Nord University, 8049, Bodø, Norway.
Truls MoumGenomics Group, Faculty of Biosciences and Aquaculture, Nord University, 8049, Bodø, Norway.
Steinar D JohansenGenomics Group, Faculty of Biosciences and Aquaculture, Nord University, 8049, Bodø, Norway. steinar.d.johansen@nord.no.
UiT The Arctic University of Norway · NONord University · NOUniversity of Oslo · NONordland Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study was to analyse intraspecific sequence variation of Atlantic cod mitochondrial DNA, based on a comprehensive collection of completely sequenced mitochondrial genomes.

resultsWe determined the complete mitochondrial DNA sequence of 124 cod specimens from the eastern and western part of the species' distribution range in the North Atlantic Ocean. All specimens harboured a unique mitochondrial DNA haplotype. Nine hundred and fifty-two polymorphic sites were identified, including 109 non-synonymous sites within protein coding regions. Eighteen variable sites were identified as indels, exclusively distributed in structural RNA genes and non-coding regions. Phylogeographic analyses based on 156 available cod mitochondrial genomes did not reveal a clear structure. There was a lack of mitochondrial genetic differentiation between two ecotypes of cod in the eastern North Atlantic, but eastern and western cod were differentiated and mitochondrial genome diversity was higher in the eastern than the western Atlantic, suggesting deviating population histories. The geographic distribution of mitochondrial genome variation seems to be governed by demographic processes and gene flow among ecotypes that are otherwise characterized by localized genomic divergence associated with chromosomal inversions.

Indexed as

AnimalsDNA, MitochondrialGadus morhuaGenomePolymorphism, Single NucleotideSequence Analysis, DNADNA, MitochondrialAtlantic codGadus morhuaGenomic resourceMitogenomemtDNASNP

Identifiers

PMID29921324
PMCPMC6009815
OpenAlexW2809202925

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.