Evidence map›Paper›PMID 29921291›Full record

Trial reportRadiation oncology (London, England)2018

Urethra-sparing stereotactic body radiotherapy for prostate cancer: how much can the rectal wall dose be reduced with or without an endorectal balloon?

Angèle Dubouloz, Michel Rouzaud, Lev Tsvang, Wilko Verbakel, Mikko Björkqvist, Nadine Linthout, Joana Lencart, Juan María Pérez-Moreno, Zeynep Ozen, Lluís Escude and 2 more

Abstract readClinical Trial, Phase IIComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Radiation oncology (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Angèle DuboulozGeneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1205, Genève, Switzerland. angele.dubouloz@hcuge.ch.ORCID http://orcid.org/0000-0002-3206-707X
Michel RouzaudGeneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1205, Genève, Switzerland.
Lev TsvangDepartment of Radiation Oncology, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Ramat Gan, Israel.
Wilko VerbakelDepartment of Radiation Oncology, VU medical center, De Boelelaan 1117, P.O. Box 7057, 1007, MB, Amsterdam, The Netherlands.
Mikko BjörkqvistDepartment of Oncology and Radiotherapy, Turku University Hospital, PO Box 52, 20521, Turku, Finland.
Nadine LinthoutOnze-Lieve-Vrouw Ziekenhuis, Moorselbaan 164, 9300, Aalst, Belgium.
Joana LencartServiço de Radioterapia Externa, Instituto Portugues de Oncologia, Rua Dr Antonio Bernardino de Almeida, 4200-072, Porto, Portugal.
Juan María Pérez-MorenoServicio de Oncología Radioterápica, Centro Integral Oncológico "Clara Campal", Hospital Universitario Madrid Sanchinarro, C/ Oña 10, 28050, Madrid, Spain.
Zeynep OzenNeolife Medical Center, Nisbetiye Mah. Yucel Sokak, No: 6 Besiktas, 34340, Istanbul, Turkey.
Lluís EscudeServei de Radiooncologia, Institut Oncològic Teknon, C/ Vilana 12, 08022, Barcelona, Spain.
Thomas ZilliGeneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1205, Genève, Switzerland.
Raymond MiralbellGeneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1205, Genève, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis is a dosimetric comparative study intended to establish appropriate low-to-intermediate dose-constraints for the rectal wall (R

methodsTen prostate cancer patients, simulated with and without an ERB, were planned to receive 36.25Gy (7.25Gyx5) to the planning treatment volume (PTV) and 32.5Gy to the urethral planning risk volume (uPRV). Reference plans with and without the ERB, optimized with respect to PTV and uPRV coverage objectives and the organs at risk dose constraints, were further optimized using a standardized stepwise approach to push down dose constraints to the R

resultsVm

conclusionsFurther optimization to the R

Indexed as

Radiotherapy Planning, Computer-AssistedHumansMaleOrgans at RiskOrgan Sparing TreatmentsProspective StudiesProstatic NeoplasmsRadiation InjuriesRadiosurgeryRadiotherapy DosageRadiotherapy, Intensity-ModulatedRectumUrethraDosimetric optimizationEndorectal balloonProstate cancerStereotactic body radiotherapyUrethra sparing

Identifiers

PMID29921291
PMCPMC6008922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.