ArticleBMC medicine2018
Simple rules for evidence translation in complex systems: A qualitative study.
Article in BMC medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
81 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Learning health system for implementation, scale-up, and sustainment: a systematic review to consolidate guidance for improvement.Implementation science : IS · 2026Pooled it
- Organisation and integrated healthcare approaches for people living with HIV, multimorbidity, or both: a systematic review.BMC public health · 2023Pooled it
- Process mapping in healthcare: a systematic review.BMC health services research · 2021Pooled it
- Bridging the Silos: A Comparative Analysis of Implementation Science and Improvement Science.Frontiers in health services · 2021Pooled it
- Learning from the emergence of NIHR Collaborations for Leadership in Applied Health Research and Care (CLAHRCs): a systematic review of evaluations.Implementation science : IS · 2018Pooled it
- An integrated, multidisciplinary management team intervention to improve patient-centeredness, HIV, and maternal-child outcomes in Lesotho: formative research on participatory implementation strategies.BMC health services research · 2024Trial
- Person-centred, integrated and pro-active care for multi-morbid elderly with advanced care needs: a propensity score-matched controlled trial.BMC health services research · 2019Trial
- Assessing fidelity to Critical Time Intervention (CTI) for homeless-experienced persons.BMC health services research · 2026Article
- Telemedicine documentation in neurology and telestroke: a global scoping review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Article
- Putting "what matters to you?" into practice: a focused team-based ethnographic study on goal-oriented care.BMC primary care · 2026Article
- Complexity of healthcare improvement - a comparative analysis of frameworks for improvement science.Frontiers in health services · 2026Article
- Integrating theory and practice: the core components guide for rigorous quality improvement design.Frontiers in health services · 2026Article
- If things were simple, word would have gotten around. Can complexity science help us improve pediatric research?Pediatric research · 2025Review
- Developing a cross-organisational physiotherapy-specific critical care competency framework to enable collaborative working: an overview of the integration journey across an academic health science centre.BMC health services research · 2025Article
- Evaluating for learning and sustainability (ELS) framework: a realist synthesis.BMC health services research · 2025Article
- Enhancing the Innovation Ecosystem: Overcoming Challenges to Introducing Information-Driven Technologies in Health Care.Journal of medical Internet research · 2025Article
- Enhancing the role of mass media in the translation of evidence from health policy and systems research in Nigeria.Health research policy and systems · 2025Article
- The Support Hospital Opioid Use Disorder Treatment (SHOUT) Texas program implementation strategy for expanding treatment for hospitalized adults with opioid use disorder.Journal of substance use and addiction treatment · 2025Article
- Survey of evidence-based nursing practice readiness for scoliosis-specific rehabilitation exercise in orthopedic nurses.Frontiers in medicine · 2025Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundEnsuring patients benefit from the latest medical and technical advances remains a major challenge, with rational-linear and reductionist approaches to translating evidence into practice proving inefficient and ineffective. Complexity thinking, which emphasises interconnectedness and unpredictability, offers insights to inform evidence translation theories and strategies. Drawing on detailed insights into complex micro-systems, this research aimed to advance empirical and theoretical understanding of the reality of making and sustaining improvements in complex healthcare systems.
methodsUsing analytical auto-ethnography, including documentary analysis and literature review, we assimilated learning from 5 years of observation of 22 evidence translation projects (UK). We used a grounded theory approach to develop substantive theory and a conceptual framework. Results were interpreted using complexity theory and 'simple rules' were identified reflecting the practical strategies that enhanced project progress.
resultsThe framework for Successful Healthcare Improvement From Translating Evidence in complex systems (SHIFT-Evidence) positions the challenge of evidence translation within the dynamic context of the health system. SHIFT-Evidence is summarised by three strategic principles, namely (1) 'act scientifically and pragmatically' - knowledge of existing evidence needs to be combined with knowledge of the unique initial conditions of a system, and interventions need to adapt as the complex system responds and learning emerges about unpredictable effects; (2) 'embrace complexity' - evidence-based interventions only work if related practices and processes of care within the complex system are functional, and evidence-translation efforts need to identify and address any problems with usual care, recognising that this typically includes a range of interdependent parts of the system; and (3) 'engage and empower' - evidence translation and system navigation requires commitment and insights from staff and patients with experience of the local system, and changes need to align with their motivations and concerns. Twelve associated 'simple rules' are presented to provide actionable guidance to support evidence translation and improvement in complex systems.
conclusionBy recognising how agency, interconnectedness and unpredictability influences evidence translation in complex systems, SHIFT-Evidence provides a tool to guide practice and research. The 'simple rules' have potential to provide a common platform for academics, practitioners, patients and policymakers to collaborate when intervening to achieve improvements in healthcare.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.