Evidence map›Paper›PMID 29921145›Full record

ArticleThe American journal of psychiatry2018

The Burden of Bereavement: Early-Onset Depression and Impairment in Youths Bereaved by Sudden Parental Death in a 7-Year Prospective Study.

Steven Pham, Giovanna Porta, Candice Biernesser, Monica Walker Payne, Satish Iyengar, Nadine Melhem, David A Brent

Erratum issued Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The American journal of psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07318090 (Developing a Family-Focused Treatment for Prolonged Grief for Parental Suicide Bereaved Families With Children), which is not on this map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
10.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07318090 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Developing a Family-Focused Treatment for Prolonged Grief for Parental Suicide Bereaved Families With Children

TypeinterventionalSponsorUniversity of PittsburghRan2025 to 2026Enrolled30ConditionsProlonged Grief Disorder (PGD)ArmsF-PGT
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 117 citations in OpenAlex.

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  10. A World That Recognises, Validates, and Supports Young People's Grief: A Co-Designed Study.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Steven PhamFrom the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children's Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Giovanna PortaFrom the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children's Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Candice BiernesserFrom the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children's Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Monica Walker PayneFrom the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children's Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Satish IyengarFrom the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children's Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Nadine MelhemFrom the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children's Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
David A BrentFrom the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children's Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
University of Pittsburgh Medical Center · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
CLINICAL RESEARCH TRAINING IN CHILD PSYCHIATRYT32MH018951 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TINA R GOLDSTEIN · 1990 to 2026
$9.7M
Impact of Sudden Parental Death on Children and FamiliesR01MH065368 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BRENT, DAVID A. · 2002 to 2012
$5.4M
NCATS NIH HHS UL1 TR001857NIMH NIH HHS R01 MH065368NIMH NIH HHS T32 MH018951
6 · The paper itself

Abstract

objectiveThe authors sought to determine the long-term impact of sudden parental death on youths and pathways between youth bereavement and impairment.

methodsYouths (N=216) who lost a parent to suicide, accident, or sudden natural death and nonbereaved youths (N=172) were followed periodically for up to 7 years. The incidence and prevalence of disorder and of functional impairment, as well as pathways to impairment, were assessed using Cox and mixed-effects logistic regression and structural equation modeling.

resultsPrior to parental death, bereaved youths had higher rates of psychiatric disorder, parental psychiatric disorder, and maltreatment. Even after adjustment for predeath risk factors, bereavement was associated with an increased incidence of depression, posttraumatic stress disorder, and functional impairment. The peak incidence of depression was in the first 2 years postbereavement, with incident depression occurring mainly in those who lost a parent at age 12 or younger. Youths bereaved by all three causes of death showed higher rates of impairment at all time points. Structural equation modeling found that bereavement had a direct effect on impairment and was also linked to impairment via its effects on early and later depression and through negative life events. Child psychiatric disorder prior to parental loss also contributed to functional impairment.

conclusionsParental death increased the incidence of depression in offspring early in the course of bereavement. Early identification and treatment of depression in bereaved youths and augmentation of family resilience may protect against later sequelae of functional impairment.

Indexed as

BereavementAdolescentCase-Control StudiesChildDepressionFemaleHumansIncidenceKaplan-Meier EstimateLogistic ModelsMaleParentsProportional Hazards ModelsProspective StudiesRisk FactorsSuicidal IdeationDepressionFunctional ImpairmentParental BereavementPTSDSudden Death

Identifiers

PMID29921145
PMCPMC6120798
OpenAlexW2808785852

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.