Evidence map›Paper›PMID 29920982›Full record

ArticleBrain and behavior2018

Effect of epidural blood injection on upright posture intolerance in patients with headaches due to intracranial hypotension: A prospective study.

Adnan I Qureshi, Danish Kherani, Muhammad A Waqas, Mushtaq H Qureshi, Faisal M Raja, Shawn S Wallery

Open access · goldAbstract readCase Reports
In one paragraph

Article in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. A Review of Spontaneous Intracranial Hypotension.Current neurology and neuroscience reports · 2019
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Adnan I QureshiZeenat Qureshi Stroke Institute, St. Cloud, Minnesota.
Danish KheraniZeenat Qureshi Stroke Institute, St. Cloud, Minnesota.ORCID 0000-0003-4904-690X
Muhammad A WaqasZeenat Qureshi Stroke Institute, St. Cloud, Minnesota.
Mushtaq H QureshiZeenat Qureshi Stroke Institute, St. Cloud, Minnesota.
Faisal M RajaUniversity of Illinois and Mercyhealth, Rockford, Illinois.
Shawn S WalleryUniversity of Illinois and Mercyhealth, Rockford, Illinois.
CentraCare Health System · USUniversity of Illinois Chicago, Rockford campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe performed a prospective study to quantify changes in various aspects of upright posture intolerance in patients with intracranial hypotension.

methodsSix patients were provided a standard questionnaire before, immediately after epidural blood patch injection and at follow-up visit within 1 month after epidural blood injection inquiring: (a) How long can they stand straight without any support? (b) Do they feel any sense of sickness when they sit or lie down after standing? (c) How long do they have to wait before they are comfortable standing again after they have stood straight? (d) How effectively and fast can they get up from sitting or lying position to stand straight? and (e) Rate their activities in upright posture without support on a standard vertical visual analogue scale between 100 (can do everything) and 0 (cannot do anything).

resultsAll patients responded that they could not stand straight for ≥30 min (four responding <5 min) on pretreatment evaluation. All patients reported improvement in this measure immediately postprocedure with two reporting ≥30 min. At follow-up, three patients reported further improvement and one patient reported worsening in this measure. The magnitude of improvement ranged from 10 to 80 points increase immediately postprocedure in their ability to perform activities, while they are standing without any support on visual analogue scale. At follow-up, four patient reported additional improvement in their ability to perform activities, while they are standing without any support (ranged from 10 to 20 points increase compared with immediately postprocedure rating).

conclusionsWe present semiquantitative data on various aspects of upright posture intolerance in patients with intracranial hypotension before and after epidural blood injection.

Indexed as

Blood Patch, EpiduralAdultFemaleHeadache DisordersHumansIntracranial HypotensionMaleMiddle AgedOrthostatic IntolerancePostureProspective StudiesSitting PositionYoung Adultcerebrospinal fluid leakageepidural blood injectionheadachesintracranial hypotension syndromeupright posture intolerancevisual analogue scale

Identifiers

PMID29920982
PMCPMC6043705
OpenAlexW2809646639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.