Evidence map›Paper›PMID 29920917›Full record

ArticleCellular microbiology2018

Lactobacillus rhamnosus GG increases cyclooxygenase-2 expression and prostaglandin E2 secretion in colonic myofibroblasts via a MyD88-dependent mechanism during homeostasis.

Gabriela Uribe, Romain Villéger, Philippe Bressollier, Rachel N Dillard, Daniel L Worthley, Timothy C Wang, Don W Powell, Maria C Urdaci, Irina V Pinchuk

Erratum issuedAbstract read
In one paragraph

Article in Cellular microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Effect ofFrontiers in microbiology · 2025
    Article
  8. Probiotic, Postbiotic, and Paraprobiotic Effects ofFoods (Basel, Switzerland) · 2024
    Review
  9. Review
  10. Gut microbes · 2023
    Article
  11. Article
  12. Review
  13. Review
  14. The Impact of Gut Microbiota on Radiation-Induced Enteritis.Frontiers in cellular and infection microbiology · 2021
    Review
  15. Article
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Gabriela UribeDepartments of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0002-9478-4293
Romain VillégerDepartments of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA.
Philippe BressollierLaboratoire de Microbiologie, Bordeaux Sciences Agro, University of Bordeaux, Gradignan, France.
Rachel N DillardDepartments of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA.
Daniel L WorthleyCancer Theme, University of Adelaide and SAHMRI, Adelaide, Australia.
Timothy C WangDepartment of Medicine, Columbia University Medical Center, New York, New York, USA.
Don W PowellDepartments of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA.
Maria C UrdaciLaboratoire de Microbiologie, Bordeaux Sciences Agro, University of Bordeaux, Gradignan, France.
Irina V PinchukDepartments of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA.

Funding

UTMB Clinical and Translational Science AwardTL1TR001440 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI HOMMEL, JONATHAN DEAN · 2015 to 2024
$3.4M
Regulatory role of CD90+ stromal cells in Th1/Th17 activity in Crohn's DiseaseR01DK103150 · NIDDK · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PINCHUK, IRYNA V · 2014 to 2017
$1.4M
NCATS NIH HHS TL1 TR001440NIDDK NIH HHS R01 DK103150
6 · The paper itself

Abstract

Prostaglandin E2 (PGE

Indexed as

Lacticaseibacillus rhamnosusAdministration, OralAnimalsArachidonate 5-LipoxygenaseArachidonic AcidCaco-2 CellsColonCyclooxygenase 2DinoprostoneHomeostasisHumansMice, Inbred C57BLMice, TransgenicMyeloid Differentiation Factor 88MyofibroblastsProbioticsArachidonate 5-LipoxygenaseArachidonic AcidCyclooxygenase 2DinoprostoneMYD88 protein, humanMyeloid Differentiation Factor 88PTGS2 protein, humanPtgs2 protein, mouseCOX-2lactic acid bacteriamechanism of actionmetabolic processesmicrobial cell interaction

Identifiers

PMID29920917
PMCPMC6202218

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.