Evidence map›Paper›PMID 29920184›Full record

ArticleNanotechnology2018

ROS-induced HepG2 cell death from hyperthermia using magnetic hydroxyapatite nanoparticles.

Chun-Ting Yang, Keng-Yuan Li, Fan-Qi Meng, Jung-Feng Lin, In-Chi Young, Robert Ivkov, Feng-Huei Lin

Open access · greenAbstract read
In one paragraph

Article in Nanotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Hydroxyapatite Biobased Materials for Treatment and Diagnosis of Cancer.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Biodegradable calcium phosphate nanoparticles for cancer therapy.Advances in colloid and interface science · 2020
    Review
  12. Review
  13. Article
  14. FeIn vivo (Athens, Greece)
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chun-Ting YangInstitute of Biomedical Engineering, National Taiwan University, No1, Section 1, Jen-Ai Rd., Taipei 100, Taiwan.
Keng-Yuan LiInstitute of Biomedical Engineering, National Taiwan University, No1, Section 1, Jen-Ai Rd., Taipei 100, Taiwan.
Fan-Qi MengDepartment of Materials Science and Engineering, National Taiwan University No. 1, Section 4, Roosevelt Road, Taipei 106, Taiwan.
Jung-Feng LinInstitute of Biomedical Engineering, National Taiwan University, No1, Section 1, Jen-Ai Rd., Taipei 100, Taiwan.
In-Chi YoungInstitute of Biomedical Engineering, National Taiwan University, No1, Section 1, Jen-Ai Rd., Taipei 100, Taiwan.
Robert IvkovDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine Baltimore, MD 21231, United States of America.
Feng-Huei LinInstitute of Biomedical Engineering, National Taiwan University, No1, Section 1, Jen-Ai Rd., Taipei 100, Taiwan.ORCID 0000-0002-2994-6671
National Taiwan University · TWJohns Hopkins University · US

Funding

Enhancing Liver Cancer Treatment With Image-Guided Magnetic HyperthermiaR01CA194574 · NCI · JOHNS HOPKINS UNIVERSITY · PI IVKOV, ROBERT · 2015 to 2019
$3.2M
NCI NIH HHS R01 CA194574
6 · The paper itself

Abstract

HepG2 cell death with magnetic hyperthermia (MHT) using hydroxyapatite nanoparticles (mHAPs) and alternating magnetic fields (AMF) was investigated in vitro. The mHAPs were synthesized as thermo-seeds by co-precipitation with the addition of Fe

Indexed as

Hyperthermia, InducedCell DeathDown-RegulationDurapatiteGene Expression Regulation, NeoplasticHep G2 CellsHumansMagnetic FieldsMagnetite Nanoparticlesp38 Mitogen-Activated Protein KinasesReactive Oxygen SpeciesUp-RegulationDurapatiteMagnetite Nanoparticlesp38 Mitogen-Activated Protein KinasesReactive Oxygen Species

Identifiers

PMID29920184
PMCPMC6931263
OpenAlexW2809277404

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.