ArticleClinical cardiology2018
Does obesity affect the outcomes in takotsubo cardiomyopathy? Analysis of the Nationwide Inpatient Sample database, 2010-2014.
Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Prognostic factors of Takotsubo cardiomyopathy: a systematic review.ESC heart failure · 2021Pooled it
- A nomogram for predicting in-hospital death in a multinational cohort of patients with takotsubo syndrome.European journal of clinical investigation · 2026Article
- Racial and Ethnic Disparities in In-Hospital Outcomes of Takotsubo Cardiomyopathy in the United States.Journal of racial and ethnic health disparities · 2026Article
- Body weight and mortality in Takotsubo syndrome: insights from the International Takotsubo (InterTAK) Registry.Open heart · 2026Observational
- Long-term prognosis in patients suffering from myocardial infarction with non-obstructive coronary arteries, ST-segment elevation myocardial infarction, infective myocarditis and tako-tsubo cardiomyopathy - all-cause mortality comparison.Archives of medical science : AMS · 2026Article
- Obesity Paradox in Takotsubo Syndrome Among Septic ICU Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Body Mass Index and Outcomes in Patients with Takotsubo Syndrome: A Nationwide Retrospective Cohort Study.Cardiology · 2024Article
- Article
- Missing Links in the Incidence of Takotsubo Cardiomyopathy in Patients with Intracerebral Hemorrhage!Neurocritical care · 2023Article
- "Obesity paradox" and takotsubo syndrome.International journal of cardiology. Cardiovascular risk and prevention · 2022Review
- Article
- Conventional cardiovascular risk factors associated with Takotsubo cardiomyopathy: A comprehensive review.Clinical cardiology · 2021Review
- Inverted U-shaped relationship between body mass index and multivessel lesions in Chinese patients with myocardial infarction: a cross-sectional study.The Journal of international medical research · 2020Article
- Racial differences in takotsubo cardiomyopathy outcomes in a large nationwide sample.ESC heart failure · 2020Article
- Takotsubo syndrome - fatal prognosis of patients with low body mass index in 5-year follow-up.Archives of medical science : AMS · 2020Article
- In-hospital Takotsubo syndrome versus in-hospital acute myocardial infarction among patients admitted for non-cardiac diseases: a nationwide inpatient database study.Heart and vessels · 2019Article
- Article
- Insular cortex lesions are not the only culprit in Takotsubo syndrome.Clinical cardiology · 2018Article
- Low prevalence of diabetes with chronic complications in patients with Takotsubo syndrome.Clinical cardiology · 2018Article
- Reply to "Low prevalence of diabetes with chronic complications in patients with Takotsubo syndrome".Clinical cardiology · 2018Article
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8 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity can lead to increased oxidative stress which is one of the proposed mechanisms in the etiopathogenesis of takotsubo cardiomyopathy (TCM). HYPOTHESIS: The presence of obesity adversely impacts clinical outcomes in TCM patients.
methodsWe queried the Nationwide Inpatient Sample database (2010-2014) to identify adult patients admitted with a principal diagnosis of TCM with and without obesity. We compared the categorical and continuous variables by Pearson χ
resultsThe study cohort comprised 612 obese TCM (weighted n = 3034) and 5696 nonobese TCM (weighted n = 28 186) patients. Obese TCM patients were more often younger and private-insurance enrollees. Cardiac complications including acute myocardial infarction (9.0% vs 7.4%; P = 0.04), cardiac arrest (2.3% vs. 0.4%; P < 0.001), cardiogenic shock (4.3% vs. 3.2%; P = 0.03), congestive heart failure (5.0% vs. 3.8%; P = 0.02), respiratory failure (12.9% vs. 11.0%; P = 0.021) and use of mechanical hemodynamic support (Impella; 0.2% vs. 0.0%, P = 0.02) were significantly higher among obese TCM patients. There were no significant differences between the 2 groups in all-cause mortality (1.0% vs. 0.8%; P = 0.35), arrhythmia (24.5% vs. 22.7%, P = 0.123), length of stay (3.7 ±3.5 vs. 3.7 ±3.6 days; P = 0.68), and total hospital charges ($40 780.16 vs. $42 575.14; P = 0.08).
conclusionsObese TCM patients were more susceptible to developing TCM-related cardiac complications than were nonobese TCM patients, without any impact on all-cause in-hospital mortality, LOS, and hospital charges.
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