ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2018
The feasibility and acceptability of mass drug administration for malaria in Cambodia: a mixed-methods study.
Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- To what extent do people in malaria-endemic countries know asymptomatic malaria infections? A systematic review.PloS one · 2026Pooled it
- A systematic review of factors influencing participation in two types of malaria prevention intervention in Southeast Asia.Malaria journal · 2021Pooled it
- Community engagement among forest goers in a malaria prophylaxis trial: implementation challenges and implications.Malaria journal · 2023Trial
- Trial
- Application Strategy and Research Progress of Large-Scale Population Drug Intervention in Malaria Control.Tropical medicine and infectious disease · 2026Review
- Operational performance of a programmatic mass drug administration campaign for malaria in southern Mozambique: a comprehensive mixed-methods evaluation of implementation outcomes.BMC public health · 2026Article
- Malária incubada: a mixed methods analysis on knowledge and experiences on Plasmodium vivax and asymptomatic malaria infections in a hard-to-reach and mobile population in the Amazon.Malaria journal · 2025Article
- Through the eyes of the participant: using photovoice to understand the experiences and effects of ivermectin MDA in the context of the BOHEMIA clinical trial in Kwale, Kenya.Malaria journal · 2025Article
- Prospective acceptability of mass drug administration for malaria in Kedougou region in Senegal: a mixed method study.Malaria journal · 2024Article
- Mass Drug Administration: Contextual Factor Considerations.The American journal of tropical medicine and hygiene · 2024Review
- Malaria infection and predictor factors among Chadian nomads' children.BMC public health · 2024Article
- Community engagement approaches for malaria prevention, control and elimination: a scoping review.BMJ open · 2024Article
- Perceptions and acceptability of co-administered albendazole, ivermectin and azithromycin mass drug administration, among the health workforce and recipient communities in Ethiopia.PLoS neglected tropical diseases · 2023Article
- Strategies for deploying triple artemisinin-based combination therapy in the Greater Mekong Subregion.Malaria journal · 2023Article
- Community acceptability, participation, and adherence to mass drug administration with primaquine for Plasmodium vivax elimination in Southern Thailand: a mixed methods approach.Malaria journal · 2023Article
- Knowledge and social beliefs of malaria and prevention strategies among itinerant Nomadic Arabs, Fulanis and Dagazada groups in Chad: a mixed method study.Malaria journal · 2022Article
- Knowledge and practices surrounding malaria and LLIN use among Arab, Dazagada and Fulani pastoral nomads in Chad.PloS one · 2022Article
- Acceptability and feasibility of malaria prophylaxis for forest goers: findings from a qualitative study in Cambodia.Malaria journal · 2021Article
- Choosing interventions to eliminate forest malaria: preliminary results of two operational research studies inside Cambodian forests.Malaria journal · 2021Article
- The promise, problems and pitfalls of mass drug administration for malaria elimination: a qualitative study with scientists and policymakers.International health · 2019Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 4 countries.
Funding
Abstract
Background: Mass drug administrations (MDAs) are part of the World Health Organization's Plasmodium falciparum elimination strategy for the Greater Mekong Subregion (GMS). In Cambodia, a 2015-2017 clinical trial evaluated the effectiveness of MDA. This article explores factors that influence the feasibility and acceptability of MDA, including seasonal timing, financial incentives and the delivery model. Methods: Quantitative data were collected through structured questionnaires from the heads of 163 households. Qualitative data were collected through 25 semi-structured interviews and 5 focus group discussions with villagers and local health staff. Calendars of village activities were created and meteorological and malaria treatment records were collected. Results: MDA delivered house-to-house or at a central point, with or without compensation, were equally acceptable and did not affect coverage. People who knew about the rationale for the MDA, asymptomatic infections and transmission were more likely to participate. In western Cambodia, MDA delivered house-to-house by volunteers at the end of the dry season may be most practicable but requires the subsequent treatment of in-migrants to prevent reintroduction of infections. Conclusions: For MDA targeted at individual villages or village clusters it is important to understand local preferences for community mobilisation, delivery and timing, as several models of MDA are feasible.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.