Evidence map›Paper›PMID 29917057›Full record

ArticleBiostatistics (Oxford, England)2019

A Bayesian space-time model for clustering areal units based on their disease trends.

Gary Napier, Duncan Lee, Chris Robertson, Andrew Lawson

Open access · hybridAbstract read
In one paragraph

Article in Biostatistics (Oxford, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Gary NapierSchool of Mathematics and Statistics, University of Glasgow, University Place, Glasgow, UK.
Duncan LeeSchool of Mathematics and Statistics, University of Glasgow, University Place, Glasgow, UK.
Chris RobertsonDepartment of Mathematics and Statistics, University of Strathclyde, 26 Richmond Street, Glasgow, UK.
Andrew LawsonDepartment of Public Health Sciences, Medical University of South Carolina, South Carolina, USA.
University of Glasgow · GBMedical University of South Carolina · USUniversity of Strathclyde · GB

Funding

Medical Research Council MR/L022184/1
6 · The paper itself

Abstract

Population-level disease risk across a set of non-overlapping areal units varies in space and time, and a large research literature has developed methodology for identifying clusters of areal units exhibiting elevated risks. However, almost no research has extended the clustering paradigm to identify groups of areal units exhibiting similar temporal disease trends. We present a novel Bayesian hierarchical mixture model for achieving this goal, with inference based on a Metropolis-coupled Markov chain Monte Carlo ((MC)$^3$) algorithm. The effectiveness of the (MC)$^3$ algorithm compared to a standard Markov chain Monte Carlo implementation is demonstrated in a simulation study, and the methodology is motivated by two important case studies in the United Kingdom. The first concerns the impact on measles susceptibility of the discredited paper linking the measles, mumps, and rubella vaccination to an increased risk of Autism and investigates whether all areas in the Scotland were equally affected. The second concerns respiratory hospitalizations and investigates over a 10 year period which parts of Glasgow have shown increased, decreased, and no change in risk.

Indexed as

AlgorithmsCluster AnalysisModels, StatisticalAutism Spectrum DisorderBayes TheoremDisease SusceptibilityHospitalizationHumansMarkov ChainsMeaslesMonte Carlo MethodRespiratory Tract DiseasesScotlandViral VaccinesViral VaccinesHealth inequalitiesMetropolis-Coupled Markov chain Monte Carlo ((MC)3) simulationSpace-time disease mappingTrend estimation

Identifiers

PMID29917057
PMCPMC6797054
OpenAlexW2808929961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.