Evidence map›Paper›PMID 29916721›Full record

ArticleThe British journal of radiology2018

Imaging peritoneal metastasis of gastric cancer with

Yoshitaka Honma, Takashi Terauchi, Ukihide Tateishi, Daisuke Kano, Kengo Nagashima, Hirokazu Shoji, Satoru Iwasa, Atsuo Takashima, Ken Kato, Tetsuya Hamaguchi and 3 more

Abstract read
In one paragraph

Article in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Impact ofJournal of cancer research and clinical oncology · 2025
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  3. Article
  4. Review
  5. Article
  6. Benign lesions withThe British journal of radiology · 2023
    Article
  7. Article
  8. Article
  9. Imaging of Gastric Carcinomatosis.Journal of clinical medicine · 2021
    Article
  10. Role of [European journal of nuclear medicine and molecular imaging · 2021
    Article
  11. Article
  12. Improving MR sequence of 18F-FDG PET/MR for diagnosing and staging gastric Cancer: a comparison study toCancer imaging : the official publication of the International Cancer Imaging Society · 2020
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Yoshitaka Honma1 Gastrointestinal Medical Oncology Division, National Cancer Center Hospital , Tokyo , Japan.
Takashi Terauchi2 Department of Nuclear Medicine, Cancer Institute Hospital, Japanese Foundation for Cancer Research , Tokyo , Japan.
Ukihide Tateishi3 Department of Diagnostic Radiology and Nuclear Medicine, Tokyo Medical and Dental University Graduate School of Medicine , Tokyo , Japan.
Daisuke Kano3 Department of Diagnostic Radiology and Nuclear Medicine, Tokyo Medical and Dental University Graduate School of Medicine , Tokyo , Japan.
Kengo Nagashima5 Department of Global Clinical Research, Graduate School of Medicine, Chiba University , Chiba , Japan.
Hirokazu Shoji1 Gastrointestinal Medical Oncology Division, National Cancer Center Hospital , Tokyo , Japan.
Satoru Iwasa1 Gastrointestinal Medical Oncology Division, National Cancer Center Hospital , Tokyo , Japan.
Atsuo Takashima1 Gastrointestinal Medical Oncology Division, National Cancer Center Hospital , Tokyo , Japan.
Ken Kato1 Gastrointestinal Medical Oncology Division, National Cancer Center Hospital , Tokyo , Japan.
Tetsuya Hamaguchi1 Gastrointestinal Medical Oncology Division, National Cancer Center Hospital , Tokyo , Japan.
Narikazu Boku1 Gastrointestinal Medical Oncology Division, National Cancer Center Hospital , Tokyo , Japan.
Yasuhiro Shimada1 Gastrointestinal Medical Oncology Division, National Cancer Center Hospital , Tokyo , Japan.
Yasuhide Yamada1 Gastrointestinal Medical Oncology Division, National Cancer Center Hospital , Tokyo , Japan.
National Cancer Center Hospital East · JPChiba University · JPHamamatsu University School of Medicine · JPJapanese Foundation For Cancer Research · JPTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePeritoneal metastasis (PM) is the most frequent form of metastasis in gastric cancer (GC). The sensitivity of detecting PM by pre-operative imaging modalities is low. Utility of positron emission tomography (PET) with

methodsThe key eligibility criteria were as follows; (i) histologically proven gastric adenocarcinoma; (ii) evident PM detected by CT performed within 4 weeks prior to registration; (iii) no prior treatment of PM within 4 weeks before registration. [F-18]FLT-PET/CT was performed at National Cancer Center Hospital, and [F-18]FLT-PET/CT images were evaluated independently by two radiologists. Safety assessments were carried out before and after [F-18]FLT-PET/CT. The primary end point was the detection sensitivity of PM.

resultsA total of 19 eligible patients were analyzed, of which 15 (78.9%) had diffuse-type histology. Detection sensitivity of PM, primary lesion, and lymph node metastasis were 73.7% [maximum standardized uptake value (SUVmax): 1.697-13.21], 100% (SUVmax: 2.71-22.01), and 72.7% (SUVmax: 2.079-12.61), respectively. No patients experienced adverse events during or after [F-18]FLT-PET/CT.

conclusionThis proof-of-concept study shows that [F-18]FLT-PET/CT is a sensitive method for detecting PM in GC, and paves the way for future studies investigating the clinical utility of this approach for the detection of clinically non-evident PM in GC. Advances in knowledge: This proof-of-concept study found that [F-18]FLT-PET/CT is a sensitive method for detecting peritoneal metastases in GC.

Indexed as

RadiopharmaceuticalsAgedFemaleFluorine RadioisotopesHumansLymphatic MetastasisMaleMiddle AgedPeritoneal NeoplasmsPositron Emission Tomography Computed TomographySensitivity and SpecificityStomach NeoplasmsThymidineFluorine RadioisotopesRadiopharmaceuticalsThymidine

Identifiers

PMID29916721
PMCPMC6223173
OpenAlexW2808765576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.