Evidence map›Paper›PMID 29916257›Full record

ArticleOrganic letters2018

Total Synthesis and Biological Activity of the Arachidonic Acid Metabolite Hemiketal E

Robert E Boer, Juan Antonio Giménez-Bastida, Olivier Boutaud, Somnath Jana, Claus Schneider, Gary A Sulikowski

Abstract read
In one paragraph

Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The Link between Prostanoids and Cardiovascular Diseases.International journal of molecular sciences · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Robert E BoerDepartment of Chemistry , Vanderbilt University, Vanderbilt Institute of Chemical Biology Nashville , Tennessee 37232 , United States.
Juan Antonio Giménez-BastidaDepartment of Pharmacology , Vanderbilt University, Vanderbilt Institute of Chemical Biology Nashville , Tennessee 37232 , United States.
Olivier BoutaudDepartment of Pharmacology , Vanderbilt University, Vanderbilt Institute of Chemical Biology Nashville , Tennessee 37232 , United States.
Somnath JanaDepartment of Chemistry , Vanderbilt University, Vanderbilt Institute of Chemical Biology Nashville , Tennessee 37232 , United States.
Claus SchneiderDepartment of Pharmacology , Vanderbilt University, Vanderbilt Institute of Chemical Biology Nashville , Tennessee 37232 , United States.ORCID 0000-0003-4215-967X
Gary A SulikowskiDepartment of Chemistry , Vanderbilt University, Vanderbilt Institute of Chemical Biology Nashville , Tennessee 37232 , United States.ORCID 0000-0002-1067-0767
Vanderbilt University · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Convergence of the COX-2 and 5-lipoxygenase pathwaysR01GM076592 · NIGMS · VANDERBILT UNIVERSITY · PI SCHNEIDER, CLAUS · 2007 to 2021
$4.0M
Chemistry and Biology of Novel Arachidonic Acid MetabolitesR01GM115722 · NIGMS · VANDERBILT UNIVERSITY · PI SULIKOWSKI, GARY ALLEN · 2015 to 2018
$1.2M
American Heart Association-American Stroke Association 16POST30690001NIDDK NIH HHS P30 DK058404NIGMS NIH HHS R01 GM076592NIGMS NIH HHS R01 GM115722
6 · The paper itself

Abstract

The total synthesis of hemiketal E

Indexed as

Arachidonic AcidBlood PlateletsHumansMolecular StructureOxidation-ReductionArachidonic Acid

Identifiers

PMID29916257
PMCPMC6425725
OpenAlexW2808913273

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.