ArticleWorld journal of microbiology & biotechnology2018
Comparative transcriptome analysis of Haematococcus pluvialis on astaxanthin biosynthesis in response to irradiation with red or blue LED wavelength.
Article in World journal of microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 49 citations in OpenAlex.
- Light-dependent processes in algae across scales: from cellular physiology to ecological organization.Plant physiology · 2026Review
- Current advancements and future prospects in the biorefinery and hyper-production of astaxanthin fromBioImpacts : BI · 2026Review
- Sensing a rainbow of colors: algal photoreceptors.Frontiers in plant science · 2025Review
- Astaxanthin: Past, Present, and Future.Marine drugs · 2023Review
- Ultrasonic Treatment Enhanced Astaxanthin Production of Haematococcus pluvialis.Journal of microbiology (Seoul, Korea) · 2023Article
- Astaxanthin as a King of Ketocarotenoids: Structure, Synthesis, Accumulation, Bioavailability and Antioxidant Properties.Marine drugs · 2023Review
- Article
- Optimization of microbial cell factories for astaxanthin production: Biosynthesis and regulations, engineering strategies and fermentation optimization strategies.Synthetic and systems biotechnology · 2022Review
- Cultivation of the microalgaeFrontiers in bioengineering and biotechnology · 2022Article
- Transcriptomic and Proteomic Characterizations of the Molecular Response to Blue Light and Salicylic Acid inMarine drugs · 2021Article
- A New Shifting Strategy in Flashing Light Based on the Cell Growth Curve to Enhance β-carotene Biosynthesis in Dunaliella salina.Current microbiology · 2021Article
- Draft Genome Sequence of the Astaxanthin-Producing Microalga Haematococcus lacustris Strain NIES-144.Microbiology resource announcements · 2020Article
- Influence of spectral intensity and quality of LED lighting on photoacclimation, carbon allocation and high-value pigments in microalgae.Photosynthesis research · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
The unicellular green microalga Haematococcus pluvialis has the highest content of the natural antioxidant, astaxanthin. Previously, it was determined that astaxanthin accumulation in H. pluvialis could be induced by blue-wavelength irradiation; however, the molecular mechanism remains unknown. The present study aimed to compare the transcriptome of H. pluvialis, with respect to astaxanthin biosynthesis, under the monochromatic red (660 nm) or blue (450 nm) light-emitting diode (LED) irradiation. Among a total of 165,372 transcripts, we identified 67,703 unigenes, of which 2245 and 171 were identified as differentially expressed genes (DEGs) in response to blue and red irradiation, respectively. Interestingly, expressional changes of blue light receptor cryptochromes were detected in response to blue and/or red LED irradiation in H. pluvialis, which may directly and indirectly regulate astaxanthin biosynthesis. In accordance with this observation, expression of the BKT and CHY genes, which are part of the downstream section of the astaxanthin biosynthetic pathway, was significantly upregulated by blue LED irradiation compared with their expression under control white irradiation. Contrastingly, they were downregulated by red LED irradiation. Our transcriptome study provided molecular insights that highlighted the different of responses of H. pluvialis to red and blue irradiation, especially for astaxanthin biosynthesis.
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