Evidence map›Paper›PMID 29916145›Full record

ArticleMolecular neurobiology2019

Vdac1 Downregulation Causes Mitochondrial Disintegration Leading to Hippocampal Neurodegeneration in Scopolamine-Induced Amnesic Mice.

Meghraj Singh Baghel, Mahendra Kumar Thakur

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
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  12. The Influence of Tyrosol-EnrichedMolecules (Basel, Switzerland) · 2022
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Meghraj Singh BaghelBiochemistry and Molecular Biology Laboratory, Department of Zoology, Brain Research Centre, Banaras Hindu University, Varanasi, 221005, India.
Mahendra Kumar ThakurBiochemistry and Molecular Biology Laboratory, Department of Zoology, Brain Research Centre, Banaras Hindu University, Varanasi, 221005, India. mkt_bhu@yahoo.com.ORCID http://orcid.org/0000-0002-0897-1712
Banaras Hindu University · IN

Funding

Department of Biotechnology BT/PR14311/MED/30/470/2010Department of Biotechnology, Ministry of Science and Technology BT/PR3996/MED/97/57/2011
6 · The paper itself

Abstract

Our previous report on hippocampal proteome analysis suggested the involvement of voltage-dependent anion channel (Vdac) 1 in scopolamine-induced amnesia. Further silencing of Vdac1 in young mice reduced the recognition memory. Vdac1 is a porin protein present abundantly on outer mitochondrial membrane. It acts as a transporter of energy metabolites ATP/ADP and Ca

Indexed as

Down-RegulationAdenosine TriphosphateAmnesiaAnimalsCatalaseHippocampusMembrane Potential, MitochondrialMiceMitochondriaNerve DegenerationReactive Oxygen SpeciesScopolamineSuperoxide DismutaseVoltage-Dependent Anion Channel 1Adenosine TriphosphateCatalaseReactive Oxygen SpeciesScopolamineSuperoxide DismutaseVoltage-Dependent Anion Channel 1ApoptosisHippocampusMitochondriaNeurodegenerationScopolamineVdac1

Identifiers

PMID29916145
OpenAlexW2809001108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.