Evidence map›Paper›PMID 29916115›Full record

ArticleEJNMMI physics2018

Reducing the number of CTs performed to monitor personalized dosimetry during peptide receptor radionuclide therapy (PRRT).

Alexandre Chicheportiche, Faozi Artoul, Arnon Schwartz, Simona Grozinsky-Glasberg, Amichay Meirovitz, David J Gross, Jeremy Godefroy

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Navigating care: understanding cancer patients' experiences with systemic radionuclide therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alexandre ChicheporticheDepartment of Nuclear Medicine and Biophysics, Hadassah-Hebrew University Medical Center, 91120, Jerusalem, Israel. alexandre@hadassah.org.il.ORCID http://orcid.org/0000-0001-7804-7421
Faozi ArtoulDepartment of Nuclear Medicine and Biophysics, Hadassah-Hebrew University Medical Center, 91120, Jerusalem, Israel.
Arnon SchwartzDepartment of Nuclear Medicine and Biophysics, Hadassah-Hebrew University Medical Center, 91120, Jerusalem, Israel.
Simona Grozinsky-GlasbergNeuroendocrine Tumor Unit, Endocrinology and Metabolism Department, Hadassah-Hebrew University Medical Center, 91120, Jerusalem, Israel.
Amichay MeirovitzOncology Department and Radiation Therapy Unit, Hadassah-Hebrew University Medical Center, 91120, Jerusalem, Israel.
David J GrossNeuroendocrine Tumor Unit, Endocrinology and Metabolism Department, Hadassah-Hebrew University Medical Center, 91120, Jerusalem, Israel.
Jeremy GodefroyDepartment of Nuclear Medicine and Biophysics, Hadassah-Hebrew University Medical Center, 91120, Jerusalem, Israel.
Hadassah Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeptide receptor radionuclide therapy (PRRT) with [

resultsThe decision whether or not to stop PRRT because of unsafe absorbed dose to the risk organs would have been the same had the classical or the new protocol been used. The agreement between the cumulative doses to the kidneys and bone marrow obtained from the two protocols was excellent with Pearson's correlation coefficients r = 0.95 and r = 0.99 (P < 0.0001) and mean relative differences of 5.30 ± 6.20% and 0.48 ± 4.88%, respectively.

conclusionsDosimetry calculations for a given patient can be done using a single CT registered to serial SPECTs. This new protocol reduces the need for a hybrid camera in the follow-up of patients receiving [

Indexed as

[177Lu]-DOTA-TATEBone marrowComputed tomography (CT)DosimetryKidneysPeptide receptor radionuclide therapy (PRRT)Single photon emission computed tomography (SPECT)

Identifiers

PMID29916115
PMCPMC6006002
OpenAlexW2807335445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.