Evidence map›Paper›PMID 29916112›Full record

ReviewNeuroscience bulletin2018

Current Status of Neuromodulatory Therapies for Disorders of Consciousness.

Xiaoyu Xia, Yi Yang, Yongkun Guo, Yang Bai, Yuanyuan Dang, Ruxiang Xu, Jianghong He

Abstract readReview
In one paragraph

Review in Neuroscience bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoyu XiaDepartment of Neurosurgery, PLA Army General Hospital, Beijing, 100700, China.
Yi YangDepartment of Neurosurgery, PLA Army General Hospital, Beijing, 100700, China.
Yongkun GuoDepartment of Neurosurgery, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450007, China.
Yang BaiInternational Vegetative State and Consciousness Science Institute, Hangzhou Normal University, Hangzhou, 311121, China.
Yuanyuan DangDepartment of Neurosurgery, PLA Army General Hospital, Beijing, 100700, China.
Ruxiang XuDepartment of Neurosurgery, PLA Army General Hospital, Beijing, 100700, China.
Jianghong HeDepartment of Neurosurgery, PLA Army General Hospital, Beijing, 100700, China. he_jianghong@sina.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment for disorders of consciousness (DOCs) is still a Gordian knot. Evidence-based guidelines on the treatment of DOC patients are not currently available, while neuromodulation techniques are seen as a potential treatment. Multiple neuromodulation therapies have been applied. This article reviews the most relevant studies in the literature in order to describe a clear picture of the current state of neuromodulation therapies that could be used to treat DOC patients. Both invasive and non-invasive brain stimulation is discussed. Significant behavioral improvements in prolonged DOCs under neuromodulation therapies are rare. The efficacy of various such therapies remains a matter of debate. Further clinical investigations of existing techniques in larger samples properly controlling for spontaneous recovery are needed, and new approaches are awaited.

Indexed as

BrainConsciousnessConsciousness DisordersHumansNeurotransmitter AgentsTranscranial Magnetic StimulationTreatment OutcomeNeurotransmitter AgentsDeep brain stimulationDisorder of consciousnessNeuromodulationRepetitive transcranial magnetic stimulationSpinal cord stimulationTranscranial direct current stimulation

Identifiers

PMID29916112
PMCPMC6060218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.