ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2018
Perinatal prediction model for severe intraventricular hemorrhage and the effect of early postnatal acidosis.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Comprehensive evaluation of risk factors for intraventricular hemorrhage in preterm neonates: a systematic review and meta-analysis.European journal of medical research · 2025Pooled it
- Predictive model for severe intraventricular hemorrhage risk in preterm infants: a systematic review and meta-analysis.Frontiers in pediatrics · 2026Review
- Impact of patent ductus arteriosus treatment on neonatal outcomes in preterm infants with or without perinatal acidosis: a nationwide cohort study.BMC pediatrics · 2025Article
- Construction and Validation of a Risk Prediction Model for Early Severe Intraventricular Hemorrhage in Very Low Birth Weight Infants.The Kaohsiung journal of medical sciences · 2025Article
- Early prediction of intraventricular hemorrhage in very low birth weight infants using deep neural networks with attention in low-resource settings.Scientific reports · 2025Article
- Intraventricular hemorrhage among very low birth weight infants in a South African cohort: a retrospective study of trends & short-term outcomes.BMC pediatrics · 2025Article
- First postnatal lactate blood levels on day 1 and outcome of preterm infants with gestational age <29 weeks.Frontiers in pediatrics · 2024Article
- A simple scoring system for prediction of IVH in very-low-birth-weight infants.Pediatric research · 2023Article
- A predictive clinical model for moderate to severe intraventricular hemorrhage in very low birth weight infants.Journal of perinatology : official journal of the California Perinatal Association · 2022Observational
- Mild Neonatal Acidemia is Associated with Neonatal Morbidity at Term.American journal of perinatology · 2021Article
- Association of Severe Retinopathy of Prematurity and Bronchopulmonary Dysplasia with Adverse Neurodevelopmental Outcomes in Preterm Infants without Severe Brain Injury.Brain sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSevere acidosis is one of the strongest predictors of neurologic outcomes in full-term infants with suspected hypoxic-ischemic encephalopathy. However, the relative importance of acidosis as a predictor of outcomes in preterm infants is much less clear. The goals of the present study were to examine the association between postnatal acidosis and severe intraventricular hemorrhage (IVH) and to establish a new score model including acid-base status after birth for predicting the risk of this morbidity.
methodsThe study sample was very low birth weight (VLBW) infants in the Korean Neonatal Network (KNN) cohort registry, collected prospectively from January 2013 to December 2014. Infants with blood pH and base deficit (BD) values collected within the first hour after birth, and documentation of severe IVH, were included. Multivariate stepwise logistic regression analysis was used to determine the contribution of postnatal acidosis to predicting severe IVH in VLBW infants. In addition, a prediction model was developed.
resultsData from 2518 VLBW infants were analyzed. Infants with postnatal acidosis had a higher incidence of severe IVH. The clinical model plus blood BD values improved predictive performance, compared with models using only perinatal data or blood pH.
conclusionsA prediction model for severe IVH was developed using the KNN registry of VLBW infants. Immediate postnatal acidosis, defined based on blood BD, was associated with a higher-risk-adjusted incidence of severe IVH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.