ArticleFunctional & integrative genomics2018
Differential expression of miR-let7a in hair follicle cycle of Liaoning cashmere goats and identification of its targets.
Article in Functional & integrative genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Hair Follicles as Micro-Organs: MicroRNA-Mediated Control of Growth, Cycling, and Fiber Traits.Biomolecules · 2026Review
- Whole-genome selection signatures identified candidate genes associated with cashmere traits in Inner Mongolia cashmere goats.Animal bioscience · 2025Article
- Multi-omics and AI-driven advances in miRNA-mediated hair follicle regulation in cashmere goats.Frontiers in veterinary science · 2025Review
- MiR-23b and miR-133 Cotarget TGFβ2/NOTCH1 in Sheep Dermal Fibroblasts, Affecting Hair Follicle Development.Cells · 2024Article
- Screening of microRNA and mRNA related to secondary hair follicle morphogenesis and development and functional analysis in cashmere goats.Functional & integrative genomics · 2022Article
- Article
- Review
- Chi-miR-370-3p regulates hair follicle morphogenesis of Inner Mongolian cashmere goats.G3 (Bethesda, Md.) · 2021Article
- Expression of miRNA-203 and its target gene in hair follicle cycle development of Cashmere goat.Cell cycle (Georgetown, Tex.) · 2021Article
- miR-149-5p Regulates Goat Hair Follicle Stem Cell Proliferation and Apoptosis by Targeting the CMTM3/AR Axis During Superior-Quality Brush Hair Formation.Frontiers in genetics · 2020Article
- Preliminary study on microR-148a and microR-10a in dermal papilla cells of Hu sheep.BMC genetics · 2019Article
- High-throughput sequencing of hair follicle development-related micrornas in cashmere goat at various fetal periods.Saudi journal of biological sciences · 2018Article
- Screening candidate microRNAs (miRNAs) in different lambskin hair follicles in Hu sheep.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
In order to improve the production and quality of Chinese cashmere, the research of hair follicle development has aroused more and more attention; the regulation mechanism of miRNA in hair follicle development has become a hot spot. A survey of transcriptome profiling screened 10 hair follicle-related miRNAs that were differentially expressed, including miR-let7a. In this study, the expression of miR-let7a was lower in anagen of hair follicle of cashmere goats than that in catagen of hair follicle of cashmere goats (p < 0.01). Results were in accordance with transcriptome data. The expression patterns of miR-let7a target genes (IGF-1R, C-myc, and FGF5) were verified by qRT-PCR, which were consistent with the results of Western blot and showed a downward trend. The dual-luciferase reporter gene system was used to verify the correlation between the expression of miR-let7a and its target genes, and it showed that miR-let7a negatively correlates with C-myc and FGF5. Present study offers new information on miRNAs and their related target genes in the regulation of hair follicle development mechanism.
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Registered trials
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