ArticleBMJ global health2018
Early changes in intervention coverage and mortality rates following the implementation of an integrated health system intervention in Madagascar.
Article in BMJ global health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Primary health care networks and impacts in low- and middle-income countries: a systematic review.Health policy and planning · 2026Pooled it
- Case fatality risk of diarrhoeal pathogens: a systematic review and meta-analysis.International journal of epidemiology · 2022Pooled it
- Persistence of geographic barriers to maternal care services following a health system strengthening initiative in rural Madagascar.BMC pregnancy and childbirth · 2025Article
- Changes in child mortality and population health following 10 years of health systems strengthening in rural Madagascar: A longitudinal cohort study.PLoS medicine · 2025Article
- Designing and Evaluating a Health System Resilient to Extreme Weather Events in Rural Madagascar.Annals of global health · 2025Article
- Networks of care to strengthen primary healthcare in resource constrained settings.BMJ (Clinical research ed.) · 2023Article
- Protocol-driven primary care and community linkage to reduce all-cause mortality in rural Zambia: a stepped-wedge cluster randomized trial.Frontiers in public health · 2023Article
- Climatic, land-use and socio-economic factors can predict malaria dynamics at fine spatial scales relevant to local health actors: Evidence from rural Madagascar.PLOS global public health · 2023Article
- Impact of health system strengthening on delivery strategies to improve child immunisation coverage and inequalities in rural Madagascar.BMJ global health · 2022Article
- Article
- Geographic barriers to care persist at the community healthcare level: Evidence from rural Madagascar.PLOS global public health · 2022Article
- Geographic barriers to achieving universal health coverage: evidence from rural Madagascar.Health policy and planning · 2021Article
- Variation in predicted COVID-19 risk among lemurs and lorises.American journal of primatology · 2021Article
- Socio-demographic, not environmental, risk factors explain fine-scale spatial patterns of diarrhoeal disease in Ifanadiana, rural Madagascar.Proceedings. Biological sciences · 2021Article
- Estimating the local spatio-temporal distribution of malaria from routine health information systems in areas of low health care access and reporting.International journal of health geographics · 2021Article
- Variation in predicted COVID-19 risk among lemurs and lorises.bioRxiv : the preprint server for biology · 2021Article
- Research priorities in maternal and neonatal health in Africa: results using the Child Health and Nutrition Research Initiative method involving over 900 experts across the continent.AAS open research · 2021Article
- District-level health system strengthening for universal health coverage: evidence from a longitudinal cohort study in rural Madagascar, 2014-2018.BMJ global health · 2020Article
- Cost and cost drivers associated with setting-up a prime vendor system to complement the national medicines supply chain in Tanzania.BMJ global health · 2020Article
- Improving geographical accessibility modeling for operational use by local health actors.International journal of health geographics · 2020Article
Corrections and comments
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Authors and funding
18 authors at 4 institutions in 4 countries.
Funding
Abstract
introductionThe Sustainable Development Goals framed an unprecedented commitment to achieve global convergence in child and maternal mortality rates through 2030. To meet those targets, essential health services must be scaled via integration with strengthened health systems. This is especially urgent in Madagascar, the country with the lowest level of financing for health in the world. Here, we present an interim evaluation of the first 2 years of a district-level health system strengthening (HSS) initiative in rural Madagascar, using estimates of intervention coverage and mortality rates from a district-wide longitudinal cohort.
methodsWe carried out a district representative household survey at baseline of the HSS intervention in over 1500 households in Ifanadiana district. The first follow-up was after the first 2 years of the initiative. For each survey, we estimated maternal, newborn and child health (MNCH) coverage, healthcare inequalities and child mortality rates both in the initial intervention catchment area and in the rest of the district. We evaluated changes between the two areas through difference-in-differences analyses. We estimated annual changes in health centre per capita utilisation from 2013 to 2016.
resultsThe intervention was associated with 19.1% and 36.4% decreases in under-five and neonatal mortality, respectively, although these were not statistically significant. The composite coverage index (a summary measure of MNCH coverage) increased by 30.1%, with a notable 63% increase in deliveries in health facilities. Improvements in coverage were substantially larger in the HSS catchment area and led to an overall reduction in healthcare inequalities. Health centre utilisation rates in the catchment tripled for most types of care during the study period.
conclusionAt the earliest stages of an HSS intervention, the rapid improvements observed for Ifanadiana add to preliminary evidence supporting the untapped and poorly understood potential of integrated HSS interventions on population health.
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