ArticleFrontiers in immunology2018
Signal Transducer and Activator of Transcription 3 Hyperactivation Associates With Follicular Helper T Cell Differentiation and Disease Activity in Rheumatoid Arthritis.
Erratum issuedOpen access · goldAbstract read
In one paragraph
Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- Regulation of follicular helper T cell subset differentiation in health and disease.Journal of molecular medicine (Berlin, Germany) · 2026Review
- Research progress on chimeric antigen receptor-based immunotherapy against autoimmune diseases.Human vaccines & immunotherapeutics · 2025Review
- Identification of MEG3 and MAPK3 as potential therapeutic targets for osteoarthritis through multiomics integration and machine learning.Scientific reports · 2025Article
- Follicular helper T cells (Tfh): heterogeneity in spatial distribution and phenotypic characteristics.Frontiers in immunology · 2025Review
- The differentiation courses of the Tfh cells: a new perspective on autoimmune disease pathogenesis and treatment.Bioscience reports · 2024Review
- Automated clustering reveals CD4Frontiers in immunology · 2023Article
- Immune surveillance and humoral immune responses in kidney transplantation - A look back at T follicular helper cells.Frontiers in immunology · 2023Review
- Advanced immunophenotyping: A powerful tool for immune profiling, drug screening, and a personalized treatment approach.Frontiers in immunology · 2023Article
- Different antibody-associated autoimmune diseases have distinct patterns of T follicular cell dysregulation.Scientific reports · 2022Article
- Increased TIGITExperimental and therapeutic medicine · 2022Article
- Targeting TNature immunology · 2022Review
- Follicular helper T cells: potential therapeutic targets in rheumatoid arthritis.Cellular and molecular life sciences : CMLS · 2021Review
- The metabolic hormone leptin promotes the function of TNature communications · 2021Article
- Effect of interleukin-6, -17, -21, -22, and -23 and STAT3 on signal transduction pathways and their inhibition in autoimmune arthritis.Immunologic research · 2021Review
- Human PD-1Frontiers in immunology · 2021Article
- Follicular Helper T Cells in the Immunopathogenesis of SARS-CoV-2 Infection.Frontiers in immunology · 2021Review
- Type 1 diabetes pathogenesis and the role of inhibitory receptors in islet tolerance.Annals of the New York Academy of Sciences · 2020Review
- Mechanism of Follicular Helper T Cell Differentiation Regulated by Transcription Factors.Journal of immunology research · 2020Review
- Regulatory Effect of Sishen Pill on Tfh Cells in Mice With Experimental Colitis.Frontiers in physiology · 2020Article
- T follicular helper cells and T follicular regulatory cells in rheumatic diseases.Nature reviews. Rheumatology · 2019Review
Corrections and comments
- Erratum issued
Authors and funding
22 authors at 8 institutions in 2 countries.
Jun DengChina-Australia Centre for Personalised Immunology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chaofan FanDepartment of Rheumatology, Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xin GaoChina-Australia Centre for Personalised Immunology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qunxiong ZengChina-Australia Centre for Personalised Immunology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ruru GuoDepartment of Rheumatology, Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yunbo WeiLaboratory of Immunology for Environment and Health, Shandong Analysis and Test Center, Qilu University of Technology, Shandong Academy of Sciences, Jinan, China.
Zhian ChenChina-Australia Centre for Personalised Immunology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yanan ChenDepartment of Rheumatology, Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Dongcheng GongChina-Australia Centre for Personalised Immunology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jia FengDepartment of Rheumatology, Affiliated Hospital of Hubei University for Nationalities, Enshi, China.
Yan XiaDepartment of Rheumatology, Affiliated Hospital of Hubei University for Nationalities, Enshi, China.
Shifei XiangDepartment of Rheumatology, Affiliated Hospital of Hubei University for Nationalities, Enshi, China.
Shushi GongDepartment of Rheumatology, Affiliated Hospital of Hubei University for Nationalities, Enshi, China.
Lin YuanHubei Provincial Key Laboratory of Occurrence and Intervention of Rheumatic Diseases, Affiliated Hospital of Hubei University for Nationalities, Enshi, China.
Wei ShenDepartment of Laboratory Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wenyan ShenDepartment of Laboratory Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lin LinDepartment of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ting JiangGuanghua Hospital of Integrative Chinese and Western Medicine, Shanghai, China.
Dongyi HeGuanghua Hospital of Integrative Chinese and Western Medicine, Shanghai, China.
Liangjing LuDepartment of Rheumatology, Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaoxiang ChenDepartment of Rheumatology, Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Di YuChina-Australia Centre for Personalised Immunology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Jiao Tong University · CNHubei University for Nationalities · CNRenji Hospital · CNHubei University · CNShanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine · CNAustralian National University · AURuijin Hospital · CNShandong Academy of Sciences · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Follicular helper T (Tfh) cells are the specialized CD4
Indexed as
AdolescentAdultAgedAged, 80 and overArthritis, RheumatoidCell DifferentiationCytokinesFemaleHumansInterleukin-6Lymphocyte ActivationMaleMiddle AgedPhosphorylationSeverity of Illness IndexSignal TransductionCytokinesInterleukin-6STAT3 Transcription Factorfollicular helper T cellsIL-6patientphosphorylationrheumatoid arthritissignal transducer and activator of transcription 3
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.